Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   NY40_RS07405 Genome accession   NZ_AP014523
Coordinates   1510167..1511951 (+) Length   594 a.a.
NCBI ID   WP_041051542.1    Uniprot ID   -
Organism   Helicobacter pylori NY40     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1505167..1516951
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NY40_RS07375 (NY40_1499) motB 1505933..1506706 (+) 774 WP_001085348.1 flagellar motor protein MotB -
  NY40_RS07380 (NY40_1500) - 1506712..1507149 (+) 438 WP_000802458.1 hypothetical protein -
  NY40_RS07385 (NY40_1501) - 1507218..1508879 (+) 1662 WP_041051536.1 ABC transporter permease/substrate-binding protein -
  NY40_RS07390 (NY40_1502) - 1508881..1509522 (+) 642 WP_041051538.1 ATP-binding cassette domain-containing protein -
  NY40_RS07395 (NY40_1503) - 1509534..1509713 (-) 180 WP_000468793.1 hypothetical protein -
  NY40_RS07400 (NY40_1504) - 1509705..1510166 (+) 462 WP_041051540.1 hypothetical protein -
  NY40_RS07405 (NY40_1505) uvrC 1510167..1511951 (+) 1785 WP_041051542.1 excinuclease ABC subunit UvrC Machinery gene
  NY40_RS07410 (NY40_1506) - 1511962..1513227 (+) 1266 WP_041051544.1 homoserine dehydrogenase -
  NY40_RS07415 (NY40_1507) - 1513227..1513571 (+) 345 WP_021174150.1 YraN family protein -
  NY40_RS07420 (NY40_1508) trxA 1513660..1513980 (+) 321 WP_000020199.1 thioredoxin -
  NY40_RS07425 (NY40_1509) trxB 1513986..1514921 (+) 936 WP_000564427.1 thioredoxin-disulfide reductase -
  NY40_RS07430 (NY40_1510) - 1515303..1516124 (+) 822 WP_041051551.1 glycosyltransferase family 25 protein -
  NY40_RS07435 (NY40_1511) - 1516339..1516587 (-) 249 WP_000790564.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68476.53 Da        Isoelectric Point: 9.5781

>NTDB_id=65798 NY40_RS07405 WP_041051542.1 1510167..1511951(+) (uvrC) [Helicobacter pylori NY40]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYSKIAKECLEMIENKDKLIKELELKMEHLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENHAFQKNSYRHYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=65798 NY40_RS07405 WP_041051542.1 1510167..1511951(+) (uvrC) [Helicobacter pylori NY40]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTACTTTTCTATTCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATCCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGACTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAGTTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAGGAGCTTGAATTAA
AAATGGAGCACCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAAACTCTTATCGGCA
CTACCATCTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACTAGAAGAGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGTGCTAAAGACATCAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGTGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTGAAAAAACGAAATTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.796

99.832

0.966

Multiple sequence alignment