Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   MKD39_RS04455 Genome accession   NZ_CP092478
Coordinates   924188..924904 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain CGMH-SH51     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 919188..929904
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MKD39_RS04435 (MKD39_04430) - 919230..920474 (+) 1245 WP_033079908.1 ammonium transporter -
  MKD39_RS04440 (MKD39_04435) - 920574..921533 (+) 960 WP_033079907.1 LacI family DNA-binding transcriptional regulator -
  MKD39_RS04445 (MKD39_04440) - 921618..923102 (+) 1485 WP_033079906.1 glycoside hydrolase family 32 protein -
  MKD39_RS04450 (MKD39_04445) - 923106..924071 (+) 966 WP_016931059.1 carbohydrate kinase family protein -
  MKD39_RS04455 (MKD39_04450) agrA 924188..924904 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  MKD39_RS04460 (MKD39_04455) agrC 924923..926206 (-) 1284 WP_033079905.1 quorum-sensing sensor histidine kinase AgrC -
  MKD39_RS04465 (MKD39_04460) agrD 926233..926373 (-) 141 WP_033079904.1 cyclic lactone autoinducer peptide AgrD -
  MKD39_RS04470 (MKD39_04465) - 926376..926942 (-) 567 WP_033079903.1 accessory gene regulator AgrB -
  MKD39_RS04475 (MKD39_04470) - 927672..928457 (-) 786 WP_011275305.1 carbon-nitrogen family hydrolase -
  MKD39_RS04480 (MKD39_04475) - 928650..929273 (-) 624 WP_011275306.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=657931 MKD39_RS04455 WP_011275301.1 924188..924904(-) (agrA) [Staphylococcus haemolyticus strain CGMH-SH51]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=657931 MKD39_RS04455 WP_011275301.1 924188..924904(-) (agrA) [Staphylococcus haemolyticus strain CGMH-SH51]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCA
ATTGGGAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCGATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACATACCCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGGTTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCCGTTCGTAATGTAAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878