Detailed information NTG0657649

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LXM97_RS09025
• Genome accession: NZ_CP092447
• Coordinates: 1882663..1883706 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SYN
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1877663..1888706

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXM97_RS08995 (LXM97_08995)	-	1878085..1879341 (-)	1257	WP_239794906.1	aminopeptidase	-
LXM97_RS09000 (LXM97_09000)	-	1879344..1879544 (-)	201	WP_000180460.1	DUF1128 family protein	-
LXM97_RS09005 (LXM97_09005)	-	1879691..1880155 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LXM97_RS09010 (LXM97_09010)	-	1880162..1880437 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LXM97_RS09015 (LXM97_09015)	-	1880715..1881931 (+)	1217	Protein_1737	YihY/virulence factor BrkB family protein	-
LXM97_RS09020 (LXM97_09020)	vraR	1882044..1882673 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
LXM97_RS09025 (LXM97_09025)	vraS	1882663..1883706 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LXM97_RS09030 (LXM97_09030)	liaF	1883703..1884404 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LXM97_RS09035 (LXM97_09035)	-	1884419..1884805 (-)	387	WP_001110179.1	hypothetical protein	-
LXM97_RS09040 (LXM97_09040)	map	1885022..1885780 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
LXM97_RS09045 (LXM97_09045)	-	1886309..1887295 (+)	987	WP_000999708.1	aromatic acid exporter family protein	-
LXM97_RS09050 (LXM97_09050)	-	1887728..1888141 (-)	414	WP_025174552.1	hypothetical protein	-
LXM97_RS09055 (LXM97_09055)	-	1888170..1888280 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=657649 LXM97_RS09025 WP_001017131.1 1882663..1883706(-) (vraS) [Staphylococcus aureus strain SYN]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=657649 LXM97_RS09025 WP_001017131.1 1882663..1883706(-) (vraS) [Staphylococcus aureus strain SYN]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1