Detailed information NTG0657471

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHB53_RS22450
• Genome accession: NZ_CP108258
• Coordinates: 4940369..4941493 (+)
• Length: 374 a.a.
• NCBI ID: WP_266673013.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00056
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4935369..4946493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHB53_RS22435 (OHB53_22380)	-	4935915..4936844 (+)	930	WP_266673019.1	hypothetical protein	-
OHB53_RS22440 (OHB53_22385)	-	4936877..4938592 (-)	1716	WP_266673017.1	BACON domain-containing protein	-
OHB53_RS22445 (OHB53_22390)	radA/sms	4938847..4940256 (+)	1410	WP_266673015.1	DNA repair protein RadA	Machinery gene
OHB53_RS22450 (OHB53_22395)	disA	4940369..4941493 (+)	1125	WP_266673013.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHB53_RS22455 (OHB53_22400)	-	4942257..4943051 (-)	795	WP_266673012.1	hypothetical protein	-
OHB53_RS22460 (OHB53_22405)	-	4943237..4943878 (+)	642	WP_266673011.1	phosphatase PAP2 family protein	-
OHB53_RS22465 (OHB53_22410)	-	4943879..4944526 (-)	648	WP_266673010.1	response regulator transcription factor	-
OHB53_RS22470 (OHB53_22415)	-	4944523..4946124 (-)	1602	WP_266673008.1	sensor histidine kinase	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40341.21 Da
• Isoelectric Point: 4.9304

>NTDB_id=657471 OHB53_RS22450 WP_266673013.1 4940369..4941493(+) (disA) [Streptomyces sp. NBC_00056]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=657471 OHB53_RS22450 WP_266673013.1 4940369..4941493(+) (disA) [Streptomyces sp. NBC_00056]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGCCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTGCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCGCAGTCGATGCGGCTCATCGCCCTCTACGTGGACGGGCAGCGGCGCGTCCTCGAGGACTCGGCCGCG
ATTCTCTCGCGGGCGAATCAGGCGCTGGCCACTCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACACTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAAATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGGCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCCGAGCGGGAGCTCGTCGTTCGGGACTACGTGCCCGAACCCACGGCCAAGCGGTCCCGGACCGTCGACGA
GGCCCTGTTCGAACTCGACGCGCTGACGCATGCCGAGCTTCTCGAACTGCCCACTGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTGGACTCGGCCGTTTCGCCTCGTGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATTGAGCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGACGATCTGCAGACCGTGGA
CGGCGTCGGCGAGGCCCGCGCCCGGAGCGTGCGGGAAGGACTCTCACGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.875	96.524	0.433