Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC   Type   Machinery gene
Locus tag   MG974_RS12785 Genome accession   NZ_CP092439
Coordinates   2627359..2628111 (-) Length   250 a.a.
NCBI ID   WP_003152643.1    Uniprot ID   A0A6A8LH02
Organism   Bacillus velezensis strain 504     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2622359..2633111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MG974_RS12760 (MG974_12760) mreC 2622794..2623657 (-) 864 WP_003152649.1 rod shape-determining protein MreC -
  MG974_RS12765 (MG974_12765) mreB 2623688..2624701 (-) 1014 WP_003152647.1 cell shape-determining protein MreB -
  MG974_RS12770 (MG974_12770) radC 2624793..2625488 (-) 696 WP_007408165.1 RadC family protein -
  MG974_RS12775 (MG974_12775) - 2625520..2626089 (-) 570 WP_032856929.1 Maf family protein -
  MG974_RS12780 (MG974_12780) - 2626231..2627232 (-) 1002 WP_003152644.1 SPOR domain-containing protein -
  MG974_RS12785 (MG974_12785) comC 2627359..2628111 (-) 753 WP_003152643.1 prepilin peptidase Machinery gene
  MG974_RS12790 (MG974_12790) - 2628251..2629543 (-) 1293 WP_060657404.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  MG974_RS12795 (MG974_12795) - 2629602..2632244 (-) 2643 WP_003152640.1 valine--tRNA ligase -
  MG974_RS12800 (MG974_12800) - 2632697..2632888 (+) 192 WP_003152639.1 hypothetical protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 27152.80 Da        Isoelectric Point: 9.2521

>NTDB_id=657454 MG974_RS12785 WP_003152643.1 2627359..2628111(-) (comC) [Bacillus velezensis strain 504]
MLLILFFLGLIFGSFFYTAACRIPLRISVISPRSSCSFCRLPLSWGELVPVVSYILQRGRCRNCRAKLSVMYPAAECWTA
CLFTAAGIHFGFSKELLVALLFLSLLMIVTMTDLQYMLIPDKVLLFFLPLFIAGRMFSPLDSWYAGFAGAVCGFFLLVFI
MFVSKGGIGAGDVKLFGVIGLTLGVKLVLIAFFLSVMIGAVYGMCAAARGSLGKKQPFPFAPAISAGSALSYLYGDELFS
FYIKLASGGA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=657454 MG974_RS12785 WP_003152643.1 2627359..2628111(-) (comC) [Bacillus velezensis strain 504]
GTGCTTTTGATTCTGTTTTTTCTCGGCTTGATTTTCGGTTCTTTTTTTTATACAGCAGCGTGCCGTATCCCGCTGCGAAT
CTCGGTTATTTCGCCGCGTTCATCCTGTTCGTTTTGCCGCTTGCCGCTCTCCTGGGGGGAGCTTGTGCCCGTCGTCTCCT
ATATTCTGCAAAGAGGCAGATGCAGAAACTGCCGTGCGAAGCTGTCGGTTATGTATCCGGCGGCGGAATGCTGGACGGCG
TGTTTATTCACGGCTGCAGGCATTCATTTCGGTTTCTCAAAAGAACTGTTAGTCGCGCTGTTATTTCTGTCTCTCCTCAT
GATTGTTACTATGACGGATCTGCAATATATGCTGATTCCTGACAAAGTTCTGCTGTTTTTTCTTCCGCTTTTCATCGCCG
GCCGTATGTTTTCTCCGCTGGATTCATGGTATGCGGGGTTTGCCGGAGCCGTTTGCGGATTTTTTCTGCTAGTTTTTATC
ATGTTTGTCAGTAAAGGAGGCATCGGCGCAGGTGATGTGAAACTGTTTGGGGTGATCGGCCTGACGCTCGGCGTGAAGCT
CGTGCTCATTGCATTCTTTCTTTCCGTTATGATCGGAGCGGTATACGGTATGTGCGCCGCAGCCCGGGGCAGTCTTGGTA
AAAAGCAGCCATTTCCGTTTGCGCCGGCCATCTCAGCCGGGAGCGCTTTGAGTTATTTATACGGTGATGAGCTGTTTTCG
TTTTACATCAAGCTCGCTTCAGGCGGGGCTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)

Type IV leader peptidase family (Peptidase_A24)

(101-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A8LH02

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC Bacillus subtilis subsp. subtilis str. 168

59.274

99.2

0.588