Detailed information NTG0657265

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: MH925_RS16655
• Genome accession: NZ_CP092412
• Coordinates: 3383710..3384873 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain HNU24
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3378710..3389873

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MH925_RS16625	-	3378975..3379394 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
MH925_RS16630	comFC	3379468..3380157 (-)	690	WP_197197403.1	phosphoribosyltransferase family protein	Machinery gene
MH925_RS16635	-	3380163..3380447 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
MH925_RS16640	comFA	3380505..3381890 (-)	1386	WP_012118573.1	DEAD/DEAH box helicase	Machinery gene
MH925_RS16645	-	3381998..3382846 (-)	849	WP_003151387.1	DegV family protein	-
MH925_RS16650	degU	3382944..3383633 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
MH925_RS16655	degS	3383710..3384873 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
MH925_RS16660	-	3385096..3385743 (+)	648	WP_007614107.1	YigZ family protein	-
MH925_RS16665	-	3385748..3386968 (+)	1221	WP_012118574.1	LCP family protein	-
MH925_RS16670	-	3387067..3388143 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
MH925_RS16675	tuaH	3388276..3389472 (-)	1197	WP_012118575.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=657265 MH925_RS16655 WP_007407484.1 3383710..3384873(-) (degS) [Bacillus velezensis strain HNU24]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=657265 MH925_RS16655 WP_007407484.1 3383710..3384873(-) (degS) [Bacillus velezensis strain HNU24]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTTAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGGGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951