Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG786_RS19410 Genome accession   NZ_CP108217
Coordinates   4538688..4539323 (+) Length   211 a.a.
NCBI ID   WP_405459332.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00101     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4533688..4544323
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG786_RS19395 (OG786_19420) - 4535529..4536212 (-) 684 WP_405459326.1 ABC transporter ATP-binding protein -
  OG786_RS19400 (OG786_19425) - 4536209..4537297 (-) 1089 WP_405459329.1 ABC transporter permease -
  OG786_RS19405 (OG786_19430) - 4537471..4538691 (+) 1221 WP_275494010.1 sensor histidine kinase -
  OG786_RS19410 (OG786_19435) vraR 4538688..4539323 (+) 636 WP_405459332.1 response regulator Regulator
  OG786_RS19415 (OG786_19440) - 4539505..4539927 (+) 423 WP_275496140.1 M67 family metallopeptidase -
  OG786_RS19420 (OG786_19445) - 4540095..4540223 (+) 129 WP_275496295.1 putative leader peptide -
  OG786_RS19425 (OG786_19450) - 4540317..4540595 (+) 279 WP_275494012.1 MoaD family protein -
  OG786_RS19430 (OG786_19455) - 4540595..4541545 (+) 951 WP_275494013.1 PLP-dependent cysteine synthase family protein -
  OG786_RS19435 (OG786_19460) - 4541703..4542215 (-) 513 WP_405459336.1 type II toxin-antitoxin system PemK/MazF family toxin -
  OG786_RS19440 (OG786_19465) - 4542447..4543199 (+) 753 WP_275494015.1 MBL fold metallo-hydrolase -
  OG786_RS19445 (OG786_19470) - 4543260..4544174 (-) 915 WP_405459338.1 hypothetical protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 21905.95 Da        Isoelectric Point: 5.3202

>NTDB_id=656538 OG786_RS19410 WP_405459332.1 4538688..4539323(+) (vraR) [Streptomyces sp. NBC_00101]
MTDTPIRLLLADDHPVVRAGLRAVLETEPGFVVTAEAATAEDAVARAAEGGIDVVLMDLQFGKGMGGAEATAQITARSGA
PRVLIVTTYDSDADTLPAIEAGATGYLLKDAPPEDLAAAVRTAAAGRTTLAPTVADRLMNRLRTPGTALTRRESEVLALV
AAGLSNQAIGNRLHLTEGTVKSHLARVYTKLDVDSRTAAVATATDLGLIRR

Nucleotide


Download         Length: 636 bp        

>NTDB_id=656538 OG786_RS19410 WP_405459332.1 4538688..4539323(+) (vraR) [Streptomyces sp. NBC_00101]
GTGACCGACACCCCCATCCGCCTGCTCCTGGCCGACGACCACCCCGTCGTACGGGCCGGACTGCGCGCCGTGCTGGAAAC
CGAACCCGGTTTCGTCGTCACCGCCGAAGCCGCCACCGCCGAGGACGCCGTCGCCCGCGCCGCCGAGGGCGGCATCGACG
TCGTGCTCATGGACCTGCAGTTCGGCAAGGGCATGGGCGGCGCCGAAGCCACCGCCCAGATCACCGCCCGCTCCGGAGCC
CCCCGCGTACTGATCGTCACCACCTACGACTCCGACGCCGACACCCTGCCCGCCATCGAAGCCGGCGCCACCGGCTACCT
CCTCAAGGACGCCCCGCCCGAGGACCTGGCGGCCGCCGTACGGACCGCGGCCGCCGGGCGCACCACACTGGCGCCCACAG
TCGCCGACCGGCTGATGAACCGGCTCCGCACACCGGGCACCGCCCTGACCCGGCGCGAGAGCGAAGTCCTCGCCCTGGTC
GCCGCCGGCCTGTCCAACCAAGCCATCGGCAACCGCCTCCACTTGACCGAAGGCACCGTCAAGTCGCACCTCGCCCGTGT
CTACACCAAACTCGACGTCGACTCCCGCACCGCCGCCGTCGCCACCGCCACCGACCTGGGACTCATCCGGCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.5

98.578

0.37