Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   MCF40_RS09065 Genome accession   NZ_CP092072
Coordinates   1923805..1924848 (-) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus argenteus strain 1710042798     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1918805..1929848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MCF40_RS09035 (MCF40_09035) - 1919216..1920463 (-) 1248 WP_000656301.1 aminopeptidase -
  MCF40_RS09040 (MCF40_09040) - 1920475..1920675 (-) 201 WP_000180459.1 DUF1128 family protein -
  MCF40_RS09045 (MCF40_09045) - 1920822..1921286 (+) 465 WP_000228669.1 low molecular weight protein-tyrosine-phosphatase -
  MCF40_RS09050 (MCF40_09050) - 1921293..1921568 (+) 276 WP_000428174.1 YtxH domain-containing protein -
  MCF40_RS09055 (MCF40_09055) - 1921847..1923070 (+) 1224 WP_000037065.1 YihY/virulence factor BrkB family protein -
  MCF40_RS09060 (MCF40_09060) vraR 1923186..1923815 (-) 630 WP_000153529.1 two-component system response regulator VraR Regulator
  MCF40_RS09065 (MCF40_09065) vraS 1923805..1924848 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  MCF40_RS09070 (MCF40_09070) liaF 1924845..1925546 (-) 702 WP_031788217.1 cell wall-active antibiotics response protein LiaF -
  MCF40_RS09075 (MCF40_09075) - 1925561..1925947 (-) 387 WP_001110170.1 hypothetical protein -
  MCF40_RS09080 (MCF40_09080) map 1926168..1926926 (-) 759 WP_031788218.1 type I methionyl aminopeptidase -
  MCF40_RS09085 (MCF40_09085) - 1927457..1928443 (+) 987 WP_031788370.1 FUSC family protein -
  MCF40_RS09090 (MCF40_09090) - 1929075..1929797 (-) 723 WP_031787877.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=655788 MCF40_RS09065 WP_001017131.1 1923805..1924848(-) (vraS) [Staphylococcus argenteus strain 1710042798]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=655788 MCF40_RS09065 WP_001017131.1 1923805..1924848(-) (vraS) [Staphylococcus argenteus strain 1710042798]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACA
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTTTGCTGCTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCATTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCAAAAGGTATTGAAGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1