Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OHU19_RS27285 Genome accession   NZ_CP108174
Coordinates   5855726..5856850 (-) Length   374 a.a.
NCBI ID   WP_116511422.1    Uniprot ID   A0ABV4SRP8
Organism   Streptomyces sp. NBC_00145     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5850726..5861850
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU19_RS27265 (OHU19_27295) - 5851389..5852285 (-) 897 WP_326711798.1 A/G-specific adenine glycosylase -
  OHU19_RS27270 (OHU19_27300) - 5852916..5853523 (+) 608 Protein_5384 response regulator transcription factor -
  OHU19_RS27275 (OHU19_27305) - 5853524..5854165 (-) 642 WP_327578210.1 phosphatase PAP2 family protein -
  OHU19_RS27280 (OHU19_27310) - 5854351..5855145 (+) 795 WP_327578211.1 hypothetical protein -
  OHU19_RS27285 (OHU19_27315) disA 5855726..5856850 (-) 1125 WP_116511422.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OHU19_RS27290 (OHU19_27320) radA/sms 5856963..5858372 (-) 1410 WP_327578212.1 DNA repair protein RadA Machinery gene
  OHU19_RS27295 (OHU19_27325) - 5858639..5860357 (+) 1719 WP_327578213.1 hypothetical protein -
  OHU19_RS27300 (OHU19_27330) - 5860391..5861320 (-) 930 WP_326711794.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40297.15 Da        Isoelectric Point: 4.9269

>NTDB_id=655417 OHU19_RS27285 WP_116511422.1 5855726..5856850(-) (disA) [Streptomyces sp. NBC_00145]
MAANDRAAAPGKSGGSSGADGLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVIDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVSFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDALTHAELLELPTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQAVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=655417 OHU19_RS27285 WP_116511422.1 5855726..5856850(-) (disA) [Streptomyces sp. NBC_00145]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGCAAGTCCGGCGGGAGCTCCGGTGCCGATGGGCTGATGCGCGCCTCACT
GAGCGCGGTCGCGCCCGGTACGGCGCTGCGTGACGGCCTCGAGCGAATCCTCCGCGGCAACACCGGCGGACTCATCGTTC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGTACCGGCGGTTTCATCCTGGACGTCGAGTTCACCGCGACGCGACTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCATCGACAAGGACATCACCAAGATCCTTCGGGCGGGCGTCCAGTTGGTGCC
CGACCCCACGATCCCCACGGAGGAGACGGGCACGCGGCACCGCACCGCGGACCGGGTGAGCAAGCAGGTCAGCTTCCCCG
TGGTCTCGGTGTCTCAGTCGATGCGGCTCATCGCCCTTTACGTGGACGGGCAGCGGCGCGTCCTCGAGGACTCGGCCGCG
ATTCTCTCGCGTGCGAATCAGGCGCTTGCCACCCTTGAGCGGTACAAGCTCCGCTTGGACGAGGTGGCCGGGACGCTCTC
CGCGCTCGAGATCGAGGATCTCGTGACCGTGCGGGATGTGACCGCGGTCGCGCAGCGGCTGGAGATGGTGCGGCGCATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTCGGGACGGATGGCCGACTGCTCGCCCTTCAGCTCGACGAGTTGATCGCC
GGGGTGGAGCCCGAGCGGGAGCTCGTCGTTCGGGACTATGTGCCCGAACCTACGGCCAAGCGGTCCCGGACCGTCGACGA
GGCGCTGTTCGAGCTCGACGCGCTGACGCATGCCGAGCTTCTCGAACTGCCCACCGTGGCACGCGCGTTGGGGTACACCG
GGTCTCCGGAGACCCTGGACTCGGCCGTTTCGCCTCGCGGGTTCCGGCTGTTGGCGAAGGTGCCTCGGCTGCCCGGGGCC
ATCATCGACCGGCTTGTCGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCCAGCGTCGATGATCTGCAGGCCGTGGA
CGGCGTCGGGGAGGCCCGTGCCCGGAGCGTGCGGGAAGGGCTCTCGCGGTTGGCCGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

44.598

96.524

0.43