Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS30575 Genome accession   NZ_CP108130
Coordinates   6726509..6727180 (+) Length   223 a.a.
NCBI ID   WP_406275726.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6721509..6732180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS30550 (OHT93_30505) - 6722330..6722938 (+) 609 WP_406275712.1 dihydrofolate reductase family protein -
  OHT93_RS30555 (OHT93_30510) - 6723024..6723587 (+) 564 WP_406275715.1 dihydrofolate reductase family protein -
  OHT93_RS30560 (OHT93_30515) - 6723658..6724206 (-) 549 WP_406275717.1 DUF1062 domain-containing protein -
  OHT93_RS30565 (OHT93_30520) - 6724925..6725143 (-) 219 WP_406275720.1 hypothetical protein -
  OHT93_RS30570 (OHT93_30525) - 6725289..6726512 (+) 1224 WP_406275723.1 sensor histidine kinase -
  OHT93_RS30575 (OHT93_30530) vraR 6726509..6727180 (+) 672 WP_406275726.1 response regulator Regulator
  OHT93_RS30580 (OHT93_30535) - 6727199..6728377 (+) 1179 WP_406275729.1 cytochrome P450 -
  OHT93_RS30585 (OHT93_30540) - 6728443..6729447 (-) 1005 WP_406275732.1 Gfo/Idh/MocA family oxidoreductase -
  OHT93_RS30590 (OHT93_30545) - 6729603..6730322 (+) 720 WP_323136086.1 GntR family transcriptional regulator -
  OHT93_RS30595 (OHT93_30550) - 6730466..6731464 (+) 999 WP_406275735.1 substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23729.28 Da        Isoelectric Point: 4.7606

>NTDB_id=654619 OHT93_RS30575 WP_406275726.1 6726509..6727180(+) (vraR) [Streptomyces sp. NBC_00191]
MTIRLLVVDDDPLVRAGLAFMFGGADDLEIVGEGADGSEVAALVDRLVPDVVLMDIRMPGTDGLTATEELRRRPDAPEVV
VLTTFHADEQVLRALRAGAAGFVLKDTAPAEIVAAVRRVAAGDPVLSPAVTRQLMTQVADRTPGTRKKSAAERIASLAER
EKEVAVAVGRGRSNAEIAATLYMSLPTVKTHVSRILAKLDLNNRVQIALLAHDAGLLDEDEPV

Nucleotide


Download         Length: 672 bp        

>NTDB_id=654619 OHT93_RS30575 WP_406275726.1 6726509..6727180(+) (vraR) [Streptomyces sp. NBC_00191]
ATGACTATCCGGTTGCTCGTCGTCGATGACGACCCTCTCGTCCGCGCGGGACTCGCCTTCATGTTCGGCGGAGCCGACGA
CCTCGAGATCGTGGGGGAGGGGGCCGACGGCTCGGAGGTCGCGGCACTCGTCGACCGGCTTGTGCCCGATGTGGTGCTGA
TGGACATCCGGATGCCGGGGACGGACGGCCTCACCGCCACTGAGGAGCTGCGCCGCCGCCCCGACGCCCCCGAAGTCGTC
GTCCTCACCACCTTCCACGCGGACGAACAGGTGCTGCGGGCGCTGCGCGCGGGAGCCGCCGGATTCGTACTGAAGGACAC
CGCGCCCGCCGAGATCGTCGCCGCGGTACGGCGGGTGGCGGCGGGCGATCCGGTGCTCTCACCGGCCGTCACCCGCCAGT
TGATGACACAGGTCGCCGACCGCACCCCCGGCACCCGCAAGAAGTCCGCCGCCGAGCGGATCGCCTCGCTCGCCGAGCGC
GAAAAGGAGGTGGCCGTCGCCGTCGGCCGCGGCAGGTCCAACGCAGAGATCGCCGCGACCCTCTATATGAGCCTGCCGAC
CGTCAAGACGCATGTCTCACGCATTCTGGCCAAGCTGGACCTGAACAACCGTGTCCAGATCGCGCTGTTGGCGCACGACG
CTGGCCTGCTCGACGAGGACGAGCCGGTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-117)

Bacterial regulatory proteins, luxR family (GerE)

(156-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.249

97.309

0.372