Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT93_RS06385 Genome accession   NZ_CP108130
Coordinates   1402532..1403152 (+) Length   206 a.a.
NCBI ID   WP_266489332.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00191     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397532..1408152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT93_RS06365 (OHT93_06330) - 1398867..1399499 (-) 633 WP_406264997.1 vitamin K epoxide reductase family protein -
  OHT93_RS06370 (OHT93_06335) - 1399637..1400491 (+) 855 WP_406264999.1 ABC transporter ATP-binding protein -
  OHT93_RS06375 (OHT93_06340) - 1400488..1401336 (+) 849 WP_406265001.1 ABC transporter permease -
  OHT93_RS06380 (OHT93_06345) - 1401294..1402535 (+) 1242 WP_406265003.1 histidine kinase -
  OHT93_RS06385 (OHT93_06350) vraR 1402532..1403152 (+) 621 WP_266489332.1 response regulator transcription factor Regulator
  OHT93_RS06390 (OHT93_06355) hisS 1403396..1404658 (-) 1263 WP_406265005.1 histidine--tRNA ligase -
  OHT93_RS06395 (OHT93_06360) - 1404670..1405377 (-) 708 WP_406265007.1 MBL fold metallo-hydrolase -
  OHT93_RS06400 (OHT93_06365) - 1405511..1406302 (+) 792 WP_406265008.1 peptidylprolyl isomerase -
  OHT93_RS06405 (OHT93_06370) - 1406480..1407709 (+) 1230 WP_406265010.1 DUF349 domain-containing protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 22016.40 Da        Isoelectric Point: 5.8653

>NTDB_id=654555 OHT93_RS06385 WP_266489332.1 1402532..1403152(+) (vraR) [Streptomyces sp. NBC_00191]
MIRILLADDHPVVREGLRGMLGAEPDLTVVGEASSGPQAEALSAELQPDIVLMDLRMPGGGGVESINRMRAAGLPCRVIV
LTTYETDTDILRAVEAGAAGYLLKDLARGELADAVRAAARGETVLAPSVAARLVDQLRRQPERPRLSERETAVLRLVAEG
CTNAEIGRRLYIGESTVKTHLLRIFGKLGVDDRTAAVTSAMRNGLL

Nucleotide


Download         Length: 621 bp        

>NTDB_id=654555 OHT93_RS06385 WP_266489332.1 1402532..1403152(+) (vraR) [Streptomyces sp. NBC_00191]
GTGATCCGCATTCTGCTCGCCGACGACCATCCCGTCGTACGGGAGGGCCTGCGCGGGATGCTCGGCGCCGAGCCCGATCT
GACCGTGGTCGGCGAGGCGTCGAGCGGACCGCAGGCGGAGGCGCTGAGCGCCGAACTCCAGCCGGACATCGTGCTGATGG
ACCTGCGGATGCCGGGCGGCGGGGGCGTCGAGTCGATCAACCGGATGCGGGCGGCAGGACTGCCCTGCCGGGTGATCGTG
CTGACGACGTACGAGACGGACACGGACATCCTGCGTGCCGTGGAGGCGGGGGCGGCGGGCTATCTGCTCAAGGACCTGGC
CCGCGGCGAACTGGCCGACGCGGTACGGGCGGCGGCTCGCGGCGAGACCGTACTGGCTCCCTCGGTGGCCGCGCGCCTGG
TCGACCAGTTGCGCCGGCAGCCGGAGCGGCCGCGGCTGTCGGAACGCGAGACGGCGGTGTTGCGGCTGGTGGCGGAGGGG
TGCACGAACGCGGAGATCGGGCGTCGGCTGTACATCGGGGAGTCGACGGTGAAGACGCACCTGTTGCGGATCTTCGGGAA
GCTGGGGGTGGACGACCGCACGGCGGCGGTGACGAGCGCGATGCGAAACGGGTTGCTGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-200)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.32

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

35.874

100

0.388