Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU08_RS06535 Genome accession   NZ_CP108128
Coordinates   1503843..1504505 (+) Length   220 a.a.
NCBI ID   WP_266854217.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00197     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1498843..1509505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU08_RS06510 (OHU08_06500) mug 1499783..1500331 (+) 549 WP_402684089.1 G/U mismatch-specific DNA glycosylase -
  OHU08_RS06515 (OHU08_06505) - 1500333..1500776 (-) 444 WP_164374768.1 hypothetical protein -
  OHU08_RS06520 (OHU08_06510) - 1500836..1501597 (-) 762 WP_406380457.1 ABC transporter permease subunit -
  OHU08_RS06525 (OHU08_06515) - 1501627..1502556 (-) 930 WP_406377562.1 ABC transporter ATP-binding protein -
  OHU08_RS06530 (OHU08_06520) - 1502665..1503828 (+) 1164 WP_406377563.1 sensor histidine kinase -
  OHU08_RS06535 (OHU08_06525) vraR 1503843..1504505 (+) 663 WP_266854217.1 response regulator transcription factor Regulator
  OHU08_RS06540 (OHU08_06530) - 1504604..1505761 (+) 1158 WP_081223159.1 ROK family protein -
  OHU08_RS06545 (OHU08_06535) - 1505885..1506646 (-) 762 WP_164374773.1 GntR family transcriptional regulator -
  OHU08_RS06550 (OHU08_06540) sigJ 1506890..1507834 (-) 945 WP_164374774.1 RNA polymerase sigma factor SigJ -
  OHU08_RS06555 (OHU08_06545) - 1508018..1508848 (+) 831 WP_351485613.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23226.83 Da        Isoelectric Point: 4.8419

>NTDB_id=654478 OHU08_RS06535 WP_266854217.1 1503843..1504505(+) (vraR) [Streptomyces sp. NBC_00197]
MPVTVLLVDDEPLVRAGLRAVLEAESDIEVVGEAADGAAVIPLVRRLRPDVVAMDVRMPLLDGIEATRAVLRTVADPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPSSVRQLAAAYGDAAGNPAARAVMERAALTER
EAQVLRLMAGGLSNAEIAARLVVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=654478 OHU08_RS06535 WP_266854217.1 1503843..1504505(+) (vraR) [Streptomyces sp. NBC_00197]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCCCTCGTACGCGCGGGCCTGCGTGCCGTGCTGGAGGCGGAGTCCGA
CATCGAGGTCGTCGGTGAGGCGGCCGACGGTGCCGCGGTGATCCCGCTGGTCCGGCGGTTACGGCCCGACGTGGTCGCCA
TGGACGTCCGGATGCCGCTGCTCGACGGCATCGAGGCCACGCGCGCGGTACTGCGGACCGTCGCCGATCCGCCGAAGATC
CTCGTGGTGACGACCTTCGAGAACGACGAGTACGTCTACGAGGCGCTGCGCGCGGGCGCCGACGGGTTCCTCCTGAAGCG
GGCGCGCCCGGCCGAGATCGTGCACGCCGTGCGGCTGGTCGCCGAGGGCGAGTCCCTGCTGTTCCCCTCCTCCGTGCGGC
AGTTGGCGGCCGCCTACGGGGACGCCGCGGGGAATCCGGCGGCGCGGGCGGTCATGGAGCGGGCCGCGCTCACCGAGCGG
GAGGCCCAGGTGCTGCGGCTGATGGCCGGAGGTCTGTCGAACGCGGAGATCGCCGCGCGGCTCGTCGTGGGCACGGAGAC
GGTCAAGTCCCACGTCAGCGCCGTACTGGCGAAGCTGGGCGCCCGGGACCGTACGCAAGCGGTCATCGCGGCGTACGAGT
CGGGCTTCGTGGCGCCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.183

99.545

0.4