Detailed information NTG0654152

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: MAK06_RS13385
• Genome accession: NZ_CP091876
• Coordinates: 2674960..2675847 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain FRI-1169
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2669960..2680847

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MAK06_RS13355 (MAK06_00515)	-	2669979..2670071 (+)	93	WP_010956583.1	hypothetical protein	-
MAK06_RS13360 (MAK06_00510)	-	2670179..2670676 (-)	498	WP_001065268.1	glutathione peroxidase	-
MAK06_RS13365 (MAK06_00505)	-	2670686..2670946 (-)	261	WP_001789910.1	hypothetical protein	-
MAK06_RS13370 (MAK06_00500)	-	2671328..2671441 (-)	114	WP_011447078.1	hypothetical protein	-
MAK06_RS13375 (MAK06_00495)	-	2672100..2674100 (-)	2001	WP_000776751.1	ABC transporter permease	-
MAK06_RS13380 (MAK06_00490)	-	2674097..2674852 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
MAK06_RS13385 (MAK06_00485)	braS	2674960..2675847 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
MAK06_RS13390 (MAK06_00480)	braR	2675858..2676523 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
MAK06_RS13395 (MAK06_00475)	-	2676549..2676749 (-)	201	WP_000604728.1	hypothetical protein	-
MAK06_RS13400 (MAK06_00470)	-	2676947..2678371 (+)	1425	WP_000953744.1	alkaline phosphatase	-
MAK06_RS13405 (MAK06_00465)	-	2678441..2678551 (+)	111	WP_001791296.1	hypothetical protein	-
MAK06_RS13410 (MAK06_00460)	-	2678654..2679109 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
MAK06_RS13415 (MAK06_00455)	-	2679354..2680115 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=654152 MAK06_RS13385 WP_000143419.1 2674960..2675847(-) (braS) [Staphylococcus aureus strain FRI-1169]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=654152 MAK06_RS13385 WP_000143419.1 2674960..2675847(-) (braS) [Staphylococcus aureus strain FRI-1169]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997