Detailed information
Bioinformatically predicted
Overview
| Name | agrA | Type | Regulator |
| Locus tag | MAK06_RS10155 | Genome accession | NZ_CP091876 |
| Coordinates | 2041594..2042310 (+) | Length | 238 a.a. |
| NCBI ID | WP_000688492.1 | Uniprot ID | A0A7U7IEW1 |
| Organism | Staphylococcus aureus strain FRI-1169 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2031425..2067059 | 2041594..2042310 | within | 0 |
Gene organization within MGE regions
Location: 2031425..2067059
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MAK06_RS10095 (MAK06_03780) | - | 2031530..2031742 (-) | 213 | WP_000128898.1 | hypothetical protein | - |
| MAK06_RS10100 (MAK06_03775) | - | 2031803..2032349 (+) | 547 | Protein_1951 | site-specific integrase | - |
| MAK06_RS10105 (MAK06_03770) | groL | 2032444..2034060 (-) | 1617 | WP_000240645.1 | chaperonin GroEL | - |
| MAK06_RS10110 (MAK06_03765) | groES | 2034136..2034420 (-) | 285 | WP_000917289.1 | co-chaperone GroES | - |
| MAK06_RS10115 (MAK06_03760) | mroQ | 2034595..2035338 (+) | 744 | WP_000197635.1 | CPBP family intramembrane glutamic endopeptidase MroQ | - |
| MAK06_RS10120 (MAK06_03755) | - | 2035363..2036616 (-) | 1254 | WP_000120307.1 | SdrH family protein | - |
| MAK06_RS10125 (MAK06_03750) | - | 2036813..2037439 (+) | 627 | WP_000522384.1 | nitroreductase family protein | - |
| MAK06_RS10130 (MAK06_03745) | - | 2037800..2038585 (+) | 786 | WP_000867960.1 | carbon-nitrogen family hydrolase | - |
| MAK06_RS10135 (MAK06_13970) | - | 2039182..2039316 (-) | 135 | WP_001549197.1 | delta-lysin family phenol-soluble modulin | - |
| MAK06_RS10140 (MAK06_03735) | agrB | 2039552..2040121 (+) | 570 | WP_001105707.1 | accessory gene regulator AgrB | - |
| MAK06_RS10145 (MAK06_03730) | - | 2040118..2040258 (+) | 141 | WP_001093929.1 | cyclic lactone autoinducer peptide | - |
| MAK06_RS10150 (MAK06_03725) | - | 2040283..2041575 (+) | 1293 | WP_001554031.1 | GHKL domain-containing protein | - |
| MAK06_RS10155 (MAK06_03720) | agrA | 2041594..2042310 (+) | 717 | WP_000688492.1 | LytTR family DNA-binding domain-containing protein | Regulator |
| MAK06_RS10160 (MAK06_03715) | - | 2042382..2042489 (+) | 108 | WP_001790167.1 | hypothetical protein | - |
| MAK06_RS10165 (MAK06_03710) | - | 2042677..2043636 (-) | 960 | WP_001253312.1 | carbohydrate kinase | - |
| MAK06_RS10170 (MAK06_03705) | - | 2043633..2045117 (-) | 1485 | WP_000141414.1 | sucrose-6-phosphate hydrolase | - |
| MAK06_RS10175 (MAK06_03700) | - | 2045266..2046216 (-) | 951 | WP_000790330.1 | LacI family DNA-binding transcriptional regulator | - |
| MAK06_RS10180 (MAK06_03695) | - | 2046399..2047649 (-) | 1251 | WP_001052270.1 | ammonium transporter | - |
| MAK06_RS10185 (MAK06_03690) | - | 2047857..2048081 (-) | 225 | WP_000581077.1 | sulfurtransferase TusA family protein | - |
| MAK06_RS10190 (MAK06_03685) | - | 2048141..2049220 (-) | 1080 | WP_000266883.1 | YeeE/YedE family protein | - |
| MAK06_RS10195 (MAK06_03680) | - | 2049524..2050159 (-) | 636 | WP_001283612.1 | redox-sensing transcriptional repressor Rex | - |
| MAK06_RS10200 (MAK06_03675) | - | 2050412..2052340 (+) | 1929 | WP_000602071.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| MAK06_RS10205 (MAK06_03670) | - | 2052485..2052613 (-) | 129 | WP_001790685.1 | hypothetical protein | - |
| MAK06_RS10210 (MAK06_03665) | - | 2052702..2054312 (+) | 1611 | WP_000106330.1 | MutS family DNA mismatch repair protein | - |
| MAK06_RS10215 (MAK06_03660) | tsaD | 2054414..2055439 (-) | 1026 | WP_000159034.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| MAK06_RS10220 (MAK06_03655) | rimI | 2055432..2055896 (-) | 465 | WP_000372758.1 | ribosomal protein S18-alanine N-acetyltransferase | - |
| MAK06_RS10225 (MAK06_03650) | tsaB | 2055869..2056531 (-) | 663 | WP_001086744.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB | - |
| MAK06_RS10230 (MAK06_03645) | tsaE | 2056512..2056973 (-) | 462 | WP_000590798.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| MAK06_RS10235 (MAK06_03640) | - | 2057011..2057166 (+) | 156 | WP_001789600.1 | hypothetical protein | - |
| MAK06_RS10240 (MAK06_03635) | ilvD | 2057484..2059172 (+) | 1689 | WP_001255791.1 | dihydroxy-acid dehydratase | - |
| MAK06_RS10245 (MAK06_03630) | ilvB | 2059200..2060969 (+) | 1770 | WP_238097445.1 | biosynthetic-type acetolactate synthase large subunit | - |
| MAK06_RS10250 (MAK06_03625) | - | 2060969..2061223 (+) | 255 | WP_000196911.1 | ACT domain-containing protein | - |
| MAK06_RS10255 (MAK06_03620) | ilvC | 2061360..2062364 (+) | 1005 | WP_000214557.1 | ketol-acid reductoisomerase | - |
| MAK06_RS10260 (MAK06_03615) | - | 2062394..2063923 (+) | 1530 | WP_000094576.1 | 2-isopropylmalate synthase | - |
| MAK06_RS10265 (MAK06_03610) | leuB | 2063926..2064972 (+) | 1047 | WP_000221958.1 | 3-isopropylmalate dehydrogenase | - |
| MAK06_RS10270 (MAK06_03605) | leuC | 2064986..2066356 (+) | 1371 | WP_000531823.1 | 3-isopropylmalate dehydratase large subunit | - |
| MAK06_RS10275 (MAK06_03600) | leuD | 2066357..2066929 (+) | 573 | WP_000718955.1 | 3-isopropylmalate dehydratase small subunit | - |
Sequence
Protein
Download Length: 238 a.a. Molecular weight: 27905.90 Da Isoelectric Point: 6.0927
>NTDB_id=654148 MAK06_RS10155 WP_000688492.1 2041594..2042310(+) (agrA) [Staphylococcus aureus strain FRI-1169]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI
Nucleotide
Download Length: 717 bp
>NTDB_id=654148 MAK06_RS10155 WP_000688492.1 2041594..2042310(+) (agrA) [Staphylococcus aureus strain FRI-1169]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| agrA | Staphylococcus aureus N315 |
100 |
100 |
1 |