Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   MAK07_RS02715 Genome accession   NZ_CP091875
Coordinates   490331..491374 (+) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus aureus strain MN8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 485331..496374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK07_RS02680 (MAK07_10470) - 485830..485940 (+) 111 WP_001790257.1 hypothetical protein -
  MAK07_RS02685 (MAK07_10465) - 485969..486382 (+) 414 WP_001643743.1 hypothetical protein -
  MAK07_RS02690 (MAK07_10460) - 486571..487557 (-) 987 WP_001014423.1 aromatic acid exporter family protein -
  MAK07_RS02695 (MAK07_14590) - 487879..488052 (+) 174 WP_001791533.1 hypothetical protein -
  MAK07_RS02700 (MAK07_10455) map 488257..489015 (+) 759 WP_000636142.1 type I methionyl aminopeptidase -
  MAK07_RS02705 (MAK07_10450) - 489232..489618 (+) 387 WP_001110178.1 hypothetical protein -
  MAK07_RS02710 (MAK07_10445) liaF 489633..490334 (+) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  MAK07_RS02715 (MAK07_10440) vraS 490331..491374 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  MAK07_RS02720 (MAK07_10435) vraR 491364..491993 (+) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  MAK07_RS02725 (MAK07_10430) - 492106..493323 (-) 1218 WP_000037081.1 YihY/virulence factor BrkB family protein -
  MAK07_RS02730 (MAK07_10425) - 493601..493876 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  MAK07_RS02735 (MAK07_10420) - 493883..494347 (-) 465 WP_000228670.1 low molecular weight protein-tyrosine-phosphatase -
  MAK07_RS02740 (MAK07_10415) - 494494..494694 (+) 201 WP_000180460.1 DUF1128 family protein -
  MAK07_RS02745 (MAK07_10410) - 494697..495953 (+) 1257 WP_001793983.1 aminopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=654075 MAK07_RS02715 WP_001017131.1 490331..491374(+) (vraS) [Staphylococcus aureus strain MN8]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=654075 MAK07_RS02715 WP_001017131.1 490331..491374(+) (vraS) [Staphylococcus aureus strain MN8]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1