Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   MAK48_RS06245 Genome accession   NZ_CP091872
Coordinates   1211012..1211668 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus sp. Man122     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1206012..1216668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MAK48_RS06215 (MAK48_06215) oppF 1206477..1207394 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  MAK48_RS06220 (MAK48_06220) - 1207501..1208718 (+) 1218 WP_010886478.1 MFS transporter -
  MAK48_RS06225 (MAK48_06225) - 1208882..1209460 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  MAK48_RS06230 (MAK48_06230) spx 1209641..1210036 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  MAK48_RS06235 (MAK48_06235) - 1210079..1210735 (-) 657 WP_003232944.1 TerC family protein -
  MAK48_RS06240 (MAK48_06240) - 1210905..1211045 (+) 141 WP_119122854.1 hypothetical protein -
  MAK48_RS06245 (MAK48_06245) mecA 1211012..1211668 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  MAK48_RS06250 (MAK48_06250) - 1211663..1211785 (-) 123 WP_003245684.1 hypothetical protein -
  MAK48_RS06255 (MAK48_06255) coiA 1211829..1212980 (+) 1152 WP_003245839.1 competence protein CoiA Machinery gene
  MAK48_RS06260 (MAK48_06260) pepF 1213210..1215039 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  MAK48_RS06265 (MAK48_06265) - 1215077..1215244 (-) 168 WP_003244944.1 hypothetical protein -
  MAK48_RS06270 (MAK48_06270) spxH 1215558..1216457 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=654016 MAK48_RS06245 WP_003245194.1 1211012..1211668(+) (mecA) [Bacillus sp. Man122]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=654016 MAK48_RS06245 WP_003245194.1 1211012..1211668(+) (mecA) [Bacillus sp. Man122]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1