Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG965_RS38450 Genome accession   NZ_CP108106
Coordinates   8605363..8606016 (+) Length   217 a.a.
NCBI ID   WP_371656722.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00224     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8600363..8611016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG965_RS38435 (OG965_38370) - 8600618..8602261 (-) 1644 WP_371656719.1 hypothetical protein -
  OG965_RS38440 (OG965_38375) - 8602385..8603488 (-) 1104 WP_371656720.1 hypothetical protein -
  OG965_RS38445 (OG965_38380) - 8604176..8605366 (+) 1191 WP_371656721.1 sensor histidine kinase -
  OG965_RS38450 (OG965_38385) vraR 8605363..8606016 (+) 654 WP_371656722.1 response regulator Regulator
  OG965_RS38455 (OG965_38390) - 8606336..8606689 (+) 354 WP_371656723.1 hypothetical protein -
  OG965_RS38460 (OG965_38395) - 8606840..8607589 (-) 750 WP_371656724.1 transposase family protein -
  OG965_RS38465 (OG965_38400) - 8607791..8608594 (+) 804 WP_371656725.1 transposase family protein -
  OG965_RS38470 (OG965_38405) - 8608967..8609653 (+) 687 WP_371656726.1 response regulator -
  OG965_RS38475 (OG965_38410) - 8609944..8610609 (+) 666 WP_371656727.1 RNA polymerase sigma factor -

Sequence

Protein


Download         Length: 217 a.a.        Molecular weight: 23705.35 Da        Isoelectric Point: 6.2715

>NTDB_id=653904 OG965_RS38450 WP_371656722.1 8605363..8606016(+) (vraR) [Streptomyces sp. NBC_00224]
MIRVLLADDDALVRQALHAMLESHDDLHVVGEARDGQEAITMARRLHPDVVLMDIRMPHLDGLAATCEITKHAGCPSVLM
LTTFDVTEYIDQALTSGADGFLLKDAPPLEVAQAIRDVAQGKAVLSNDITLQIVHLVRDRSRAFLGIDRDLLPSLTNRER
DILPLIAQGRSNAEIGHRLHVSEATVKAHVSRLLIKLDVGNRVQLAILAHRAGLAGE

Nucleotide


Download         Length: 654 bp        

>NTDB_id=653904 OG965_RS38450 WP_371656722.1 8605363..8606016(+) (vraR) [Streptomyces sp. NBC_00224]
ATGATTCGCGTCCTGCTCGCCGACGACGATGCCTTGGTTCGCCAAGCCTTGCACGCCATGCTCGAATCCCACGACGACCT
GCACGTCGTCGGCGAGGCACGGGACGGTCAGGAGGCCATCACCATGGCCCGTCGCCTCCACCCGGACGTCGTGCTCATGG
ATATCCGCATGCCCCACCTCGACGGCCTGGCCGCCACCTGTGAGATCACGAAACACGCGGGCTGCCCCAGCGTGCTCATG
CTCACCACGTTCGATGTCACCGAGTACATCGACCAGGCACTGACGAGTGGTGCCGACGGCTTCCTGCTCAAAGACGCCCC
GCCCCTGGAAGTCGCCCAAGCCATCCGTGATGTCGCTCAGGGCAAGGCTGTCCTGTCGAACGACATCACCCTGCAGATCG
TGCACCTCGTCCGGGATCGTAGCCGCGCCTTCCTGGGCATCGACCGCGACTTGCTCCCCTCACTCACCAACCGAGAACGC
GACATCCTGCCTCTCATCGCACAGGGCAGATCCAACGCCGAGATCGGCCACAGACTCCACGTCAGCGAAGCCACTGTCAA
AGCCCACGTCAGCCGGCTACTCATCAAACTGGACGTCGGAAACAGGGTCCAACTCGCGATCCTCGCCCACCGCGCCGGCC
TGGCCGGCGAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.559

98.157

0.369