Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG446_RS12405 Genome accession   NZ_CP108100
Coordinates   2778572..2779234 (+) Length   220 a.a.
NCBI ID   WP_328894087.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00236     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2773572..2784234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG446_RS12385 (OG446_12400) - 2774570..2775349 (-) 780 WP_328894083.1 phosphatase -
  OG446_RS12390 (OG446_12405) - 2775556..2776827 (+) 1272 WP_328894084.1 APC family permease -
  OG446_RS12395 (OG446_12410) - 2776841..2777215 (-) 375 WP_328894085.1 DUF6223 family protein -
  OG446_RS12400 (OG446_12415) - 2777448..2778575 (+) 1128 WP_328894086.1 sensor histidine kinase -
  OG446_RS12405 (OG446_12420) vraR 2778572..2779234 (+) 663 WP_328894087.1 response regulator transcription factor Regulator
  OG446_RS12410 (OG446_12425) - 2779260..2779565 (-) 306 WP_328894088.1 PadR family transcriptional regulator -
  OG446_RS12415 (OG446_12430) - 2779735..2780361 (-) 627 WP_328894089.1 TetR/AcrR family transcriptional regulator -
  OG446_RS12420 (OG446_12435) - 2780494..2782101 (+) 1608 WP_328894090.1 carboxyl transferase domain-containing protein -
  OG446_RS12425 (OG446_12440) - 2782109..2784193 (+) 2085 WP_328894091.1 acetyl-CoA carboxylase biotin carboxylase subunit -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23911.49 Da        Isoelectric Point: 4.6184

>NTDB_id=653592 OG446_RS12405 WP_328894087.1 2778572..2779234(+) (vraR) [Streptomyces sp. NBC_00236]
MIRVLLVDDQPLLRSGFRALLDLEDDIEVVAEAADGEECLALVEEHLPDVALIDIQMPVMDGIEATRRIAADPALAGVHV
VMLTNYGMDEYVLDALRAGAAGFLVKDILPEDFLHAVRVAARGDALLAPAITRKLIDRYVTQRPSTRADSGLEELTGRER
EAVALAAQGLSNSEIGEHMVIAPLTAKTHINRAMAKLHARDRAQLVVLAYESGLVTPRDH

Nucleotide


Download         Length: 663 bp        

>NTDB_id=653592 OG446_RS12405 WP_328894087.1 2778572..2779234(+) (vraR) [Streptomyces sp. NBC_00236]
GTGATCCGTGTCCTGCTGGTCGACGACCAGCCGCTCCTGCGCAGCGGCTTCCGCGCGCTGCTCGACCTCGAAGACGACAT
CGAGGTGGTGGCCGAGGCCGCCGACGGCGAGGAGTGCCTGGCGCTCGTCGAGGAGCATCTGCCCGATGTCGCGCTCATCG
ACATCCAGATGCCTGTCATGGACGGCATCGAAGCGACCCGCCGCATCGCCGCGGACCCGGCCCTGGCCGGTGTGCACGTC
GTCATGCTGACCAACTACGGCATGGACGAGTACGTTCTCGACGCGCTGCGCGCCGGCGCCGCGGGCTTCCTCGTCAAGGA
CATCCTTCCGGAGGACTTCCTGCACGCCGTACGCGTCGCCGCCCGCGGTGACGCCCTGCTCGCGCCCGCGATCACACGCA
AGCTCATCGACCGCTACGTCACCCAGCGCCCCTCCACCCGCGCCGACAGCGGGCTGGAGGAACTCACCGGCCGCGAACGC
GAGGCGGTCGCCCTCGCCGCACAGGGACTGTCCAACAGCGAGATCGGCGAGCACATGGTCATCGCCCCGTTGACCGCCAA
GACCCACATCAACCGGGCCATGGCCAAGCTCCACGCCCGCGACCGCGCCCAGCTCGTGGTCCTTGCCTACGAATCCGGCC
TGGTGACACCGCGCGACCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.318

97.273

0.373