Detailed information NTG0653524

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG764_RS16415
• Genome accession: NZ_CP108095
• Coordinates: 3749897..3751021 (+)
• Length: 374 a.a.
• NCBI ID: WP_328969159.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00239
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3744897..3756021

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG764_RS16400 (OG764_16395)	-	3745330..3746175 (+)	846	WP_328969156.1	hypothetical protein	-
OG764_RS16405 (OG764_16400)	-	3746340..3748202 (-)	1863	WP_328969157.1	hypothetical protein	-
OG764_RS16410 (OG764_16405)	radA/sms	3748340..3749785 (+)	1446	WP_328969158.1	DNA repair protein RadA	Machinery gene
OG764_RS16415 (OG764_16410)	disA	3749897..3751021 (+)	1125	WP_328969159.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG764_RS16420 (OG764_16415)	-	3751173..3752000 (-)	828	WP_328969160.1	hypothetical protein	-
OG764_RS16425 (OG764_16420)	-	3752159..3752764 (+)	606	WP_328969161.1	phosphatase PAP2 family protein	-
OG764_RS16430 (OG764_16425)	-	3752793..3753770 (+)	978	WP_328969162.1	A/G-specific adenine glycosylase	-
OG764_RS16435 (OG764_16430)	-	3753942..3754502 (+)	561	WP_328969163.1	SigE family RNA polymerase sigma factor	-
OG764_RS16440 (OG764_16435)	-	3754538..3755155 (+)	618	WP_328969164.1	hypothetical protein	-
OG764_RS16445 (OG764_16440)	cseB	3755165..3755866 (+)	702	WP_328969165.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40467.40 Da
• Isoelectric Point: 5.1240

>NTDB_id=653524 OG764_RS16415 WP_328969159.1 3749897..3751021(+) (disA) [Streptomyces sp. NBC_00239]
MAAKDGAAASGKSGASSRHEALMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKAVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIHTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVDEALAELDLLTHAELLELPVVARALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=653524 OG764_RS16415 WP_328969159.1 3749897..3751021(+) (disA) [Streptomyces sp. NBC_00239]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCCGGCGCGAGCTCCAGACACGAGGCCCTGATGCGTGCCTCGCT
GAGCGCGGTCGCCCCTGGTCAGCCCCTGCGTGACGGGCTGGAGCGGATCGTCCGCGGCAACACCGGCGGGCTGATCGTCC
TGGGCATGGACAAGGCCGTCGAGTCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGCCTGCGC
GAGCTGTGCAAGCTCGACGGTGCGCTCATCCTCGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
GGACGCGTCGATCCACACCGAGGAGACCGGCACCCGGCACCGCACCGCCGACCGCGTCTCCAAGCAGTGCGGCTTCCCGG
TGGTGTCGGTCTCGCAGTCCATGCGCCTGATCGCGCTGTACGTGGACGGCGAGCGCCGGGTGCTGGAGGAGTCCGGGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTGGCCACGCTGGAGCGGTACAAGCTGCGCCTGGACGAGGTGGCGGGCACCCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGATGTCACGGCGGTCGCGCAGCGGCTGGAAATGGTGCGCCGGATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTCGGCACGGACGGCCGGCTGCTGTCGCTCCAGCTGGACGAGCTGACGGTC
GGCATCGAGCAGGAGCGCGAGCTGGTCATCCGCGACTACGTCCCGGAGCCGACGGCGAAGCGTTCCCGCACGGTGGACGA
GGCGCTCGCCGAGCTGGACCTGCTGACCCACGCCGAGCTGCTCGAACTGCCCGTCGTGGCGCGGGCGCTGGGGTACACGG
GCTCGCCCGAGACCCTCGACTCGGCGGTCTCGCCGCGCGGTTACCGGCTGCTGGCGAAGGTGCCGCGGCTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCGGCGAGCGTCGACGACCTGCAGACGGTCGA
CGGCGTCGGCGAGGCGCGCGCCCGCAGCGTCCGCGAGGGCCTGTCCCGGCTGGCCGAGTCCTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.706	96.524	0.441