Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   L6503_RS00550 Genome accession   NZ_CP091770
Coordinates   113060..114844 (-) Length   594 a.a.
NCBI ID   WP_237775759.1    Uniprot ID   -
Organism   Helicobacter pylori strain K115     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 108060..119844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L6503_RS00520 (L6503_00520) - 108454..108702 (+) 249 WP_000790557.1 RNA-binding protein -
  L6503_RS00525 (L6503_00525) - 108910..109731 (-) 822 WP_237775756.1 glycosyltransferase family 25 protein -
  L6503_RS00530 (L6503_00530) trxB 110089..111024 (-) 936 WP_097687835.1 thioredoxin-disulfide reductase -
  L6503_RS00535 (L6503_00535) trxA 111030..111350 (-) 321 WP_000020204.1 thioredoxin -
  L6503_RS00540 (L6503_00540) - 111439..111783 (-) 345 WP_237775757.1 YraN family protein -
  L6503_RS00545 (L6503_00545) - 111784..113049 (-) 1266 WP_237775758.1 homoserine dehydrogenase -
  L6503_RS00550 (L6503_00550) uvrC 113060..114844 (-) 1785 WP_237775759.1 excinuclease ABC subunit UvrC Machinery gene
  L6503_RS00555 (L6503_00555) - 114845..115306 (-) 462 WP_220965258.1 hypothetical protein -
  L6503_RS00560 (L6503_00560) - 115298..115477 (+) 180 WP_000468796.1 hypothetical protein -
  L6503_RS00565 (L6503_00565) - 115489..116130 (-) 642 WP_237775760.1 ATP-binding cassette domain-containing protein -
  L6503_RS00570 (L6503_00570) - 116134..117795 (-) 1662 Protein_113 ABC transporter permease/substrate-binding protein -
  L6503_RS00575 (L6503_00575) - 117975..118412 (-) 438 WP_001031792.1 hypothetical protein -
  L6503_RS00580 (L6503_00580) motB 118416..119183 (-) 768 WP_180461182.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68748.05 Da        Isoelectric Point: 9.7098

>NTDB_id=653518 L6503_RS00550 WP_237775759.1 113060..114844(-) (uvrC) [Helicobacter pylori strain K115]
MADLLSSLKNLSHSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRASLRIQMMIKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQLHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKISNEDLILEEARSLFKLECMPYRVEIFDT
SHHSSSQCVGGMVVYENHAFQKDSYRRYHLKGSNEYTQMSELLSRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=653518 L6503_RS00550 WP_237775759.1 113060..114844(-) (uvrC) [Helicobacter pylori strain K115]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGTTATTTTTCTGTCCGTAATAATGAAATCACACCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGATCAAGCAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGACAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
GTTAGTGAAGATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATTGCATTTGCCTTTAATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAATCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCTAGCAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGCATTTCAAAAAGACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCAGCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATCGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGAAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97