Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT59_RS09945 Genome accession   NZ_CP108094
Coordinates   2256021..2256692 (-) Length   223 a.a.
NCBI ID   WP_326719784.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00243     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2251021..2261692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT59_RS09925 (OHT59_09930) - 2251585..2252589 (-) 1005 WP_326719781.1 sugar ABC transporter substrate-binding protein -
  OHT59_RS09930 (OHT59_09935) - 2252835..2253572 (-) 738 WP_326725980.1 GntR family transcriptional regulator -
  OHT59_RS09935 (OHT59_09940) - 2253701..2254711 (+) 1011 WP_326719782.1 Gfo/Idh/MocA family oxidoreductase -
  OHT59_RS09940 (OHT59_09945) - 2254796..2255980 (-) 1185 WP_326719783.1 cytochrome P450 -
  OHT59_RS09945 (OHT59_09950) vraR 2256021..2256692 (-) 672 WP_326719784.1 response regulator transcription factor Regulator
  OHT59_RS09950 (OHT59_09955) - 2256986..2258293 (-) 1308 WP_326719785.1 histidine kinase -
  OHT59_RS09955 (OHT59_09960) - 2258590..2258796 (+) 207 WP_326719786.1 hypothetical protein -
  OHT59_RS09960 (OHT59_09965) - 2258847..2259239 (-) 393 WP_326719787.1 ribonuclease domain-containing protein -
  OHT59_RS09965 (OHT59_09970) - 2259391..2260017 (-) 627 WP_326719788.1 dihydrofolate reductase family protein -
  OHT59_RS09970 (OHT59_09975) - 2260129..2260956 (-) 828 WP_326719789.1 AIM24 family protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23805.32 Da        Isoelectric Point: 5.3390

>NTDB_id=653400 OHT59_RS09945 WP_326719784.1 2256021..2256692(-) (vraR) [Streptomyces sp. NBC_00243]
MTVIRLLLVDDDPLVRAGLSFMMGGADDIEIVGEAADGSEVAALVDRTRPDVVLMDIRMPNVDGLTATEQLRARKDAPQV
VVLTTFHADDQVLRALRAGAAGFVLKDTPPTEILAAVRRVAAGDPVLSPTVTRQLMAHAAGSALDTRRSGARTRIAALND
REREVAVAVGQGRANAEIATQLFMSVATVKTHVSRILAKLDLNNRVQIALLTYDAGLLEEDGH

Nucleotide


Download         Length: 672 bp        

>NTDB_id=653400 OHT59_RS09945 WP_326719784.1 2256021..2256692(-) (vraR) [Streptomyces sp. NBC_00243]
ATGACTGTGATCCGACTGCTCCTTGTCGACGACGACCCCCTGGTGCGGGCCGGCCTGTCCTTCATGATGGGCGGCGCCGA
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGGAGCGAGGTCGCGGCCCTCGTCGACCGCACCCGCCCGGACGTCGTCC
TCATGGACATCCGGATGCCGAACGTCGACGGACTCACGGCCACCGAGCAGCTGCGCGCACGCAAGGACGCTCCCCAGGTC
GTCGTCCTCACCACCTTCCACGCCGACGACCAGGTACTGCGGGCGCTGCGCGCGGGCGCGGCCGGGTTCGTTCTCAAGGA
CACCCCGCCGACTGAGATCCTCGCGGCGGTACGACGGGTCGCCGCGGGCGATCCAGTGCTCTCGCCCACTGTGACCCGCC
AGTTGATGGCCCACGCCGCCGGCTCCGCCCTCGACACCCGGCGGTCGGGCGCCCGCACGAGGATCGCCGCTCTGAACGAC
CGCGAGCGTGAGGTCGCCGTGGCCGTCGGGCAGGGCAGGGCGAACGCCGAGATCGCCACCCAACTCTTCATGAGCGTCGC
CACCGTAAAGACCCATGTCTCGCGGATCCTCGCCAAGCTCGACCTCAACAACCGCGTACAGATCGCCCTGTTGACGTACG
ACGCCGGACTGCTCGAAGAGGACGGGCACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.986

98.206

0.363