Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   OHT77_RS25365 Genome accession   NZ_CP108087
Coordinates   5757887..5758945 (-) Length   352 a.a.
NCBI ID   WP_328834341.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5752887..5763945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS25340 (OHT77_25345) cseB 5753139..5753846 (-) 708 WP_328830754.1 two-component system response regulator CseB -
  OHT77_RS25345 (OHT77_25350) - 5753992..5754585 (-) 594 WP_328834340.1 hypothetical protein -
  OHT77_RS25350 (OHT77_25355) - 5754669..5755208 (-) 540 WP_019064956.1 SigE family RNA polymerase sigma factor -
  OHT77_RS25355 (OHT77_25360) - 5755509..5756450 (-) 942 WP_328830755.1 A/G-specific adenine glycosylase -
  OHT77_RS25360 (OHT77_25365) - 5756941..5757840 (+) 900 WP_328830756.1 hypothetical protein -
  OHT77_RS25365 (OHT77_25370) disA 5757887..5758945 (-) 1059 WP_328834341.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  OHT77_RS25370 (OHT77_25375) radA/sms 5759083..5760492 (-) 1410 WP_266769766.1 DNA repair protein RadA Machinery gene
  OHT77_RS25375 (OHT77_25380) - 5760691..5762388 (+) 1698 WP_328830757.1 hypothetical protein -
  OHT77_RS25380 (OHT77_25385) - 5762392..5763249 (-) 858 WP_328830758.1 hypothetical protein -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38034.67 Da        Isoelectric Point: 4.7751

>NTDB_id=653203 OHT77_RS25365 WP_328834341.1 5757887..5758945(-) (disA) [Streptomyces sp. NBC_00252]
MRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPDIPTEETGTRHRTADRVSKQVAFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVVQRLEMVRLIATEIAEYVVELGTDGRLLALQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVDEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=653203 OHT77_RS25365 WP_328834341.1 5757887..5758945(-) (disA) [Streptomyces sp. NBC_00252]
ATGCGCGCCTCACTGAGCGCCGTGGCCCCCGGCACGGCGTTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGTTCCGACAAGACCGTCGAAGCGATGTGCACGGGCGGCTTCATCCTGGACGTCGAGTTCACGG
CCACGCGCCTGCGCGAACTGTGCAAGCTCGACGGCGGCATCGTGGTGTCGTCCGACCTCTCCAAGATCCTCCGGGCGGGC
GTCCAGCTGGTCCCCGACCCGGACATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGCGTCAGCAAACA
GGTCGCCTTCCCGGTGGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCCCTCTACGTGGACGGCCAGCGACGCGTCCTGG
AGGACTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCCCTGGCGACGCTGGAGCGCTACAAGCTCCGGCTGGACGAGGTG
GCGGGAACGTTGTCAGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCCGCGGTGGTCCAGCGGCTGGAGAT
GGTCCGGCTGATCGCCACCGAAATCGCCGAGTACGTAGTGGAGTTGGGCACGGACGGCCGCCTGCTCGCCCTCCAGCTGG
AGGAGTTGATCGCGGGCGTGGAGCCGGAGCGCGAACTCGTCGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGATCC
CGCACGGTGGACGAGGCACTCGCCGAACTCGACGCCCTCTCCCACGCGGAGCTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGTTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTCTCCCCCCGCGGCTTCCGTCTGCTGGCCAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTCGAGCACTTCGGCGGCCTGCAGAAACTCCTGGCGGCAAGCGTCGACGAC
CTGCAGACGGTCGACGGCGTGGGCGAAGCGCGGGCACGCAGCGTCCGAGAGGGCCTCTCCCGCCTGGCGGAGTCCTCGAT
CCTCGAACGCTACGTCTGA

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.665

98.295

0.449