Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS15245 Genome accession   NZ_CP108087
Coordinates   3560958..3561620 (-) Length   220 a.a.
NCBI ID   WP_328828954.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3555958..3566620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS15220 (OHT77_15205) - 3556176..3556973 (+) 798 WP_328828948.1 hypothetical protein -
  OHT77_RS15225 (OHT77_15210) - 3557248..3558041 (+) 794 WP_328834246.1 IS5 family transposase -
  OHT77_RS15230 (OHT77_15215) - 3558075..3558446 (+) 372 WP_328828950.1 BlaI/MecI/CopY family transcriptional regulator -
  OHT77_RS15235 (OHT77_15220) - 3559212..3559892 (-) 681 WP_328828952.1 hypothetical protein -
  OHT77_RS15240 (OHT77_15225) - 3559889..3560395 (-) 507 WP_328828953.1 sigma-70 family RNA polymerase sigma factor -
  OHT77_RS15245 (OHT77_15230) vraR 3560958..3561620 (-) 663 WP_328828954.1 response regulator transcription factor Regulator
  OHT77_RS15250 (OHT77_15235) - 3561617..3562780 (-) 1164 WP_328828956.1 histidine kinase -
  OHT77_RS15255 (OHT77_15240) - 3562898..3563698 (+) 801 WP_328828957.1 hypothetical protein -
  OHT77_RS15260 (OHT77_15245) - 3564026..3564388 (+) 363 WP_328828959.1 BlaI/MecI/CopY family transcriptional regulator -
  OHT77_RS15265 (OHT77_15250) - 3564385..3565314 (+) 930 WP_328828960.1 M48 family metalloprotease -
  OHT77_RS15270 (OHT77_15255) - 3565462..3566340 (-) 879 WP_328828961.1 ABC transporter permease -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24159.99 Da        Isoelectric Point: 6.9830

>NTDB_id=653180 OHT77_RS15245 WP_328828954.1 3560958..3561620(-) (vraR) [Streptomyces sp. NBC_00252]
MTVSVLLADDQALIRMAFRSLLDTMPDITVVGEAANGQEAVDLTRRTRPDAVLMDVRMPVMDGIEATRRITSHTASRVLI
LTTFDLDEYAFEGLRAGACGFLLKDVVPAVLQAAIRAVASGDAVLTPRITRGLVDRFAQIAPWPRADDAGALFARLTARE
KDVFHLIAAGLSNAEIAERLFLTEATVKTHITRILTKLQLRDRVQVVIFAYEHQLRTHGG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=653180 OHT77_RS15245 WP_328828954.1 3560958..3561620(-) (vraR) [Streptomyces sp. NBC_00252]
ATGACGGTTTCGGTTCTCCTCGCCGACGACCAGGCACTCATCCGCATGGCCTTCCGCAGCCTCCTCGACACGATGCCGGA
CATCACCGTCGTCGGCGAAGCCGCCAACGGACAGGAAGCGGTCGACCTCACGCGGCGCACGCGGCCGGACGCGGTGCTCA
TGGACGTACGCATGCCCGTCATGGACGGCATCGAAGCGACCCGCCGCATCACCTCCCACACAGCCTCCCGCGTCCTCATC
CTCACCACCTTCGACCTCGACGAGTACGCCTTCGAGGGCCTCCGCGCCGGTGCCTGCGGATTCCTCCTCAAGGACGTCGT
CCCGGCCGTGCTCCAGGCGGCGATCCGGGCCGTGGCCTCCGGCGACGCCGTCCTCACCCCGCGCATCACCCGCGGTCTCG
TCGACCGCTTCGCCCAGATCGCCCCGTGGCCCCGCGCAGACGACGCAGGCGCACTCTTCGCCCGACTGACGGCCCGCGAA
AAGGACGTGTTCCACCTCATCGCCGCCGGACTGTCGAACGCGGAGATCGCCGAACGTCTCTTCCTCACCGAGGCCACCGT
CAAGACCCACATCACCCGCATCCTCACCAAACTGCAGCTCCGCGACCGGGTCCAGGTCGTCATCTTCGCCTACGAACACC
AGCTGCGCACGCACGGCGGATAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

98.182

0.382