Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT77_RS09480 Genome accession   NZ_CP108087
Coordinates   2190243..2190923 (-) Length   226 a.a.
NCBI ID   WP_328827693.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00252     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2185243..2195923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT77_RS09460 (OHT77_09450) - 2186429..2187166 (-) 738 WP_266776865.1 GntR family transcriptional regulator -
  OHT77_RS09465 (OHT77_09455) - 2187297..2188313 (+) 1017 WP_328827688.1 Gfo/Idh/MocA family oxidoreductase -
  OHT77_RS09470 (OHT77_09460) - 2188333..2188719 (-) 387 Protein_1885 PaaI family thioesterase -
  OHT77_RS09475 (OHT77_09465) - 2188993..2190177 (-) 1185 WP_328827691.1 cytochrome P450 -
  OHT77_RS09480 (OHT77_09470) vraR 2190243..2190923 (-) 681 WP_328827693.1 response regulator transcription factor Regulator
  OHT77_RS09485 (OHT77_09475) - 2191092..2192339 (-) 1248 WP_328827695.1 histidine kinase -
  OHT77_RS09490 (OHT77_09480) - 2192568..2192957 (+) 390 WP_328827697.1 ribonuclease domain-containing protein -
  OHT77_RS09495 (OHT77_09485) - 2193121..2194173 (-) 1053 WP_328834196.1 hypothetical protein -
  OHT77_RS09500 (OHT77_09490) - 2194321..2194647 (-) 327 WP_266773996.1 hypothetical protein -
  OHT77_RS09505 (OHT77_09495) - 2194815..2195774 (+) 960 WP_328827698.1 STM4015 family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24071.53 Da        Isoelectric Point: 4.6887

>NTDB_id=653164 OHT77_RS09480 WP_328827693.1 2190243..2190923(-) (vraR) [Streptomyces sp. NBC_00252]
MTAIRLLLVDDDPLVRAGLSFMLGGAADIEIVGEAADGSEVEELVDRVHPDVVLMDIRMPSMDGLTATERLRARGDAPQI
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEILDAVRRVAAGDPVLSPAVTRQLMEHAAGTTTDTRRARARERIAALGE
REREVAVAVGQGLANAEIATGLFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLIEEDGESGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=653164 OHT77_RS09480 WP_328827693.1 2190243..2190923(-) (vraR) [Streptomyces sp. NBC_00252]
ATGACTGCGATCAGACTGCTCCTCGTCGACGACGACCCGCTGGTGCGGGCCGGGCTGTCCTTCATGCTGGGCGGCGCCGC
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGCAGCGAGGTCGAGGAGCTCGTCGACCGCGTCCACCCGGACGTCGTCC
TGATGGACATCCGCATGCCCTCCATGGACGGACTGACCGCCACGGAACGGCTCCGCGCCCGCGGTGACGCGCCCCAGATC
GTCGTCCTCACCACCTTCCACGCCGACGAACAGGTGCTGCGGGCCCTCCGCGCGGGCGCCGCCGGCTTCGTCCTCAAGGA
CACCCCGCCCGCCGAGATCCTCGACGCGGTACGCCGGGTCGCGGCCGGCGATCCCGTGCTGTCGCCCGCGGTCACCCGCC
AGCTGATGGAACACGCGGCCGGCACCACCACCGACACCCGCCGGGCACGCGCGCGTGAGCGCATCGCCGCCCTGGGGGAG
CGCGAACGCGAGGTCGCCGTCGCCGTCGGTCAGGGCCTCGCCAACGCCGAGATCGCCACCGGCCTCTTCATGAGCGTCGC
CACCGTGAAGACCCATGTCTCCCGCATCCTGGCCAAGCTCGACCTCAACAACCGGGTGCAGATCGCCCTGTTGGCCTACG
ACGCGGGCCTGATCGAAGAGGACGGGGAGAGCGGGCACTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(7-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.991

96.46

0.376