Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS16060 Genome accession   NZ_CP108081
Coordinates   3601173..3601853 (+) Length   226 a.a.
NCBI ID   WP_143638530.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3596173..3606853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS16040 (OG718_16025) - 3596176..3596718 (-) 543 WP_143638538.1 MarR family transcriptional regulator -
  OG718_RS16045 (OG718_16030) - 3596955..3597407 (+) 453 WP_143638536.1 MarR family transcriptional regulator -
  OG718_RS16050 (OG718_16035) - 3597618..3599828 (+) 2211 WP_328844451.1 MMPL family transporter -
  OG718_RS16055 (OG718_16040) - 3599945..3601126 (+) 1182 WP_143638532.1 sensor histidine kinase -
  OG718_RS16060 (OG718_16045) vraR 3601173..3601853 (+) 681 WP_143638530.1 response regulator transcription factor Regulator
  OG718_RS16065 (OG718_16050) - 3601895..3602617 (-) 723 WP_143638528.1 DUF1775 domain-containing protein -
  OG718_RS16070 (OG718_16055) - 3602581..3603267 (-) 687 WP_328844452.1 hypothetical protein -
  OG718_RS16075 (OG718_16060) - 3603471..3603950 (-) 480 WP_143638524.1 hypothetical protein -
  OG718_RS16080 (OG718_16065) - 3603928..3604479 (-) 552 WP_143638522.1 ATP-binding protein -
  OG718_RS16085 (OG718_16070) - 3604856..3605731 (+) 876 WP_143638520.1 helix-turn-helix transcriptional regulator -
  OG718_RS16090 (OG718_16075) - 3605772..3605984 (+) 213 WP_186001225.1 DUF397 domain-containing protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24096.63 Da        Isoelectric Point: 4.9329

>NTDB_id=652973 OG718_RS16060 WP_143638530.1 3601173..3601853(+) (vraR) [Streptomyces sp. NBC_00258]
MTIRVLLADDQALLRATFRILIDSCDDMEVVGEATDGKEAVELTHTHRPDVVLMDIRMPGSDGLGATTAICADPDLSGTR
VLILTTFETDEYVARALRAGASGFLGKDVTADVLLDGIRTVSVGESLLSPLATRSLITRFLAAPAPADRLATPERLATLT
SRERQVMALAAEGRSNDEIAESLVVSPLTVRTHVHRAMTKLGARDRAQLVVIAYQSGLVQAPPPAS

Nucleotide


Download         Length: 681 bp        

>NTDB_id=652973 OG718_RS16060 WP_143638530.1 3601173..3601853(+) (vraR) [Streptomyces sp. NBC_00258]
ATGACCATCCGCGTCCTGCTCGCCGACGACCAAGCCCTGCTGAGAGCGACCTTCCGGATCCTGATCGACTCCTGCGACGA
CATGGAGGTGGTCGGCGAGGCCACGGACGGCAAGGAGGCGGTCGAACTCACCCACACACACCGCCCCGACGTCGTGCTCA
TGGACATCCGGATGCCCGGCTCGGACGGTCTGGGCGCCACCACCGCGATCTGCGCCGACCCGGATCTCTCGGGCACTCGG
GTCCTCATCCTCACGACCTTCGAGACCGACGAGTACGTGGCCCGGGCCCTGCGCGCCGGCGCGAGCGGCTTCCTCGGCAA
GGACGTCACCGCCGATGTGCTCCTCGACGGCATCCGGACGGTGTCCGTCGGCGAGTCCCTGCTCTCCCCGCTCGCCACGC
GCTCCCTCATCACCCGTTTCCTCGCCGCCCCCGCACCCGCCGACCGGCTGGCGACACCCGAGCGCCTCGCCACTCTCACC
TCCCGCGAACGGCAGGTCATGGCGCTGGCAGCCGAGGGCAGGTCCAACGACGAGATCGCCGAGAGCCTCGTCGTCAGCCC
CCTGACCGTACGTACGCACGTGCATCGCGCGATGACGAAGCTGGGCGCCCGCGACCGGGCCCAACTGGTCGTCATCGCCT
ACCAGTCCGGACTCGTGCAGGCCCCGCCGCCCGCGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(158-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.727

97.345

0.367