Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG718_RS14810 Genome accession   NZ_CP108081
Coordinates   3303026..3303697 (-) Length   223 a.a.
NCBI ID   WP_143641033.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3298026..3308697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG718_RS14790 (OG718_14785) - 3298587..3299591 (-) 1005 WP_328844335.1 sugar ABC transporter substrate-binding protein -
  OG718_RS14795 (OG718_14790) - 3299731..3300468 (-) 738 WP_143641065.1 GntR family transcriptional regulator -
  OG718_RS14800 (OG718_14795) - 3300598..3301611 (+) 1014 WP_143641031.1 Gfo/Idh/MocA family oxidoreductase -
  OG718_RS14805 (OG718_14800) - 3301797..3302984 (-) 1188 WP_328844336.1 cytochrome P450 -
  OG718_RS14810 (OG718_14805) vraR 3303026..3303697 (-) 672 WP_143641033.1 response regulator transcription factor Regulator
  OG718_RS14815 (OG718_14810) - 3303827..3305092 (-) 1266 WP_306936694.1 histidine kinase -
  OG718_RS14820 (OG718_14815) - 3305263..3305466 (+) 204 WP_306936695.1 hypothetical protein -
  OG718_RS14825 (OG718_14820) - 3305506..3305898 (-) 393 WP_328844338.1 ribonuclease -
  OG718_RS14830 (OG718_14825) - 3306029..3306658 (-) 630 WP_328844339.1 dihydrofolate reductase family protein -
  OG718_RS14835 (OG718_14830) - 3306917..3307666 (+) 750 WP_328844340.1 3-oxoacyl-ACP reductase family protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 23869.27 Da        Isoelectric Point: 5.1234

>NTDB_id=652972 OG718_RS14810 WP_143641033.1 3303026..3303697(-) (vraR) [Streptomyces sp. NBC_00258]
MTPIRLLLVDDDPLVRAGLSFMMGGADDLEIVGEAADGSEVEALVDRTRPDVVLMDIRMPTVDGLAATERLRSRKDAPQV
IVLTTFHADDQVLRALRAGAGGFVLKDTPPAEILDAVRRVAAGDPVLSPTVTRQLMAHAAGTSADTRRTSARTRVATLND
REREVAVAVGQGRSNAEIATGLFMSVATVKTHVSRILAKLDLNNRVQIALLTYDAGLLEEDGH

Nucleotide


Download         Length: 672 bp        

>NTDB_id=652972 OG718_RS14810 WP_143641033.1 3303026..3303697(-) (vraR) [Streptomyces sp. NBC_00258]
ATGACTCCGATCCGTCTGCTCCTCGTCGACGACGACCCACTGGTCAGGGCCGGCCTCTCCTTCATGATGGGCGGCGCCGA
CGACCTCGAGATCGTGGGGGAGGCCGCCGACGGCAGCGAGGTCGAGGCGCTGGTCGACCGCACGCGCCCGGACGTCGTCC
TCATGGACATCCGTATGCCCACGGTGGACGGACTGGCGGCCACCGAACGGCTCAGGAGTCGCAAGGACGCCCCGCAGGTC
ATCGTCCTGACCACCTTTCACGCCGACGACCAGGTGCTGCGGGCGCTGCGCGCGGGCGCGGGCGGCTTCGTCCTCAAGGA
CACCCCGCCCGCGGAGATCCTCGACGCGGTACGCCGGGTCGCGGCCGGCGATCCCGTGCTCTCGCCCACCGTGACGCGGC
AGTTGATGGCCCACGCCGCGGGCACCTCGGCCGACACCCGGCGCACGAGCGCCCGTACGCGCGTCGCCACGCTCAACGAC
CGTGAGCGTGAGGTGGCCGTCGCCGTGGGCCAGGGCCGTTCGAACGCCGAGATCGCGACCGGACTGTTCATGAGCGTCGC
CACCGTCAAGACGCACGTCTCCCGCATCCTCGCCAAGCTCGACCTCAACAACCGTGTGCAGATCGCCCTGTTGACGTACG
ACGCCGGACTCCTGGAGGAGGACGGGCACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.986

98.206

0.363