Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA28_RS36180 Genome accession   NZ_CP108075
Coordinates   7977498..7978160 (-) Length   220 a.a.
NCBI ID   WP_326713794.1    Uniprot ID   A0ABV4SFG4
Organism   Streptomyces sp. NBC_00269     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7972498..7983160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA28_RS36145 (OHA28_36175) - 7972642..7973352 (-) 711 WP_326713789.1 winged helix-turn-helix domain-containing protein -
  OHA28_RS36150 (OHA28_36180) - 7973396..7974043 (-) 648 WP_326713790.1 TetR/AcrR family transcriptional regulator -
  OHA28_RS36155 (OHA28_36185) - 7974124..7975275 (+) 1152 WP_326713791.1 acyl-CoA dehydrogenase family protein -
  OHA28_RS36160 (OHA28_36190) - 7975416..7975706 (+) 291 WP_326713792.1 YiaA/YiaB family inner membrane protein -
  OHA28_RS36165 (OHA28_36195) - 7975781..7976419 (+) 639 WP_266668800.1 TetR/AcrR family transcriptional regulator -
  OHA28_RS36170 (OHA28_36200) - 7976432..7976893 (-) 462 WP_266566073.1 MaoC family dehydratase -
  OHA28_RS36175 (OHA28_36205) soxR 7977019..7977486 (+) 468 WP_326713793.1 redox-sensitive transcriptional activator SoxR -
  OHA28_RS36180 (OHA28_36210) vraR 7977498..7978160 (-) 663 WP_326713794.1 response regulator transcription factor Regulator
  OHA28_RS36185 (OHA28_36215) - 7978157..7979377 (-) 1221 WP_326713795.1 sensor histidine kinase -
  OHA28_RS36190 (OHA28_36220) - 7979511..7980449 (+) 939 WP_326713796.1 ATP-binding cassette domain-containing protein -
  OHA28_RS36195 (OHA28_36225) - 7980446..7981288 (+) 843 WP_326713797.1 ABC transporter permease -
  OHA28_RS36200 (OHA28_36230) - 7981411..7981923 (+) 513 WP_326713798.1 hypothetical protein -
  OHA28_RS36205 (OHA28_36235) - 7982031..7982633 (-) 603 WP_326713799.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23387.89 Da        Isoelectric Point: 4.6363

>NTDB_id=652770 OHA28_RS36180 WP_326713794.1 7977498..7978160(-) (vraR) [Streptomyces sp. NBC_00269]
MTVRVVLADDQPLVRSGLRVLIADTPDLEVVGEAANGEEAVRLAREVSPDVIVMDIRMPGMNGIEATSLVTSGPGATRVL
VLTTFDEDDYVYGALRAGASGFAVKDMALDDILAAIRVVAAGDALIAPGITRRLIADFVGRPEPSPARAPRAVEGITERE
REVLTLVGLGRSNSEIAEELYITVATTKSHVARLFTKLGARDRVQLVIIAYESGLVSAPR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=652770 OHA28_RS36180 WP_326713794.1 7977498..7978160(-) (vraR) [Streptomyces sp. NBC_00269]
ATGACCGTGCGCGTGGTGCTCGCCGACGACCAGCCGCTCGTGCGCTCCGGGCTGCGCGTCCTCATCGCCGACACCCCCGA
TCTGGAGGTCGTCGGGGAGGCCGCGAACGGTGAGGAGGCCGTCCGGCTGGCGAGGGAGGTCAGCCCCGATGTGATCGTGA
TGGACATCCGGATGCCGGGCATGAACGGGATCGAGGCCACGAGCCTGGTCACCTCGGGCCCGGGGGCGACCCGTGTGCTG
GTGCTGACGACCTTCGACGAGGACGACTACGTCTACGGCGCGCTGCGCGCCGGCGCGAGCGGCTTCGCGGTCAAGGACAT
GGCGCTCGACGACATCCTCGCCGCGATCCGGGTCGTCGCCGCCGGGGACGCGCTGATCGCGCCGGGGATCACGCGCCGCC
TCATCGCCGACTTCGTGGGCCGCCCCGAGCCGTCCCCCGCCCGCGCGCCGCGTGCGGTGGAGGGCATCACCGAGCGGGAG
CGCGAGGTGCTGACGCTGGTGGGGCTCGGCCGGTCGAACAGCGAGATCGCCGAAGAGCTGTACATCACCGTGGCCACGAC
CAAGTCGCACGTGGCCCGCCTGTTCACCAAACTGGGCGCCCGGGACCGGGTCCAACTCGTCATCATCGCCTACGAGTCGG
GGCTGGTCTCCGCGCCCCGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.788

98.636

0.373