Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG827_RS36490 Genome accession   NZ_CP108068
Coordinates   7917113..7917778 (+) Length   221 a.a.
NCBI ID   WP_328764746.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00272     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7912113..7922778
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG827_RS36470 (OG827_36490) - 7912926..7913927 (-) 1002 WP_327280330.1 PHB depolymerase family esterase -
  OG827_RS36475 (OG827_36495) - 7914013..7914981 (+) 969 WP_327280331.1 LysR family transcriptional regulator -
  OG827_RS36480 (OG827_36500) - 7914978..7915910 (+) 933 WP_327280332.1 serine hydrolase -
  OG827_RS36485 (OG827_36505) - 7915920..7917116 (+) 1197 WP_327280333.1 sensor histidine kinase -
  OG827_RS36490 (OG827_36510) vraR 7917113..7917778 (+) 666 WP_328764746.1 response regulator transcription factor Regulator
  OG827_RS36495 (OG827_36515) - 7917897..7918196 (+) 300 WP_327280335.1 SHOCT domain-containing protein -
  OG827_RS36500 (OG827_36520) - 7918239..7918745 (-) 507 WP_327280336.1 GNAT family N-acetyltransferase -
  OG827_RS36505 (OG827_36525) - 7918907..7919665 (+) 759 WP_327280337.1 carbonic anhydrase -
  OG827_RS36510 (OG827_36530) - 7919787..7920455 (+) 669 WP_328764747.1 hemerythrin domain-containing protein -
  OG827_RS36515 (OG827_36535) - 7920452..7921174 (-) 723 WP_327280339.1 beta-glucanase -
  OG827_RS36520 (OG827_36540) - 7921258..7921662 (-) 405 WP_327280340.1 DUF5997 family protein -
  OG827_RS36525 (OG827_36545) - 7921751..7922584 (+) 834 WP_328764748.1 LysR family substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23781.55 Da        Isoelectric Point: 4.7984

>NTDB_id=652604 OG827_RS36490 WP_328764746.1 7917113..7917778(+) (vraR) [Streptomyces sp. NBC_00272]
MIRVLLADDQALVRAGFRALLDAQPDIEVAGEAADGAEAVRLARELRPDIALMDIRMPELDGLAATRTITGDPGLGAVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVAGDALLSPGVTRRLIGEFAARSKAPEAAAELERLTERER
EVMALVGMGLSNEEIARRLVVSPLTAKTHVSRAMIKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652604 OG827_RS36490 WP_328764746.1 7917113..7917778(+) (vraR) [Streptomyces sp. NBC_00272]
TTGATCCGGGTACTGCTCGCCGACGACCAGGCGCTGGTACGGGCCGGCTTCCGCGCGCTGCTGGACGCGCAGCCGGACAT
CGAGGTCGCGGGCGAGGCCGCCGACGGGGCCGAGGCCGTGCGCCTGGCACGCGAACTGCGCCCGGACATCGCCCTGATGG
ACATCCGGATGCCGGAGCTCGACGGCCTGGCCGCCACCCGCACGATCACCGGGGACCCGGGGCTGGGCGCCGTGAAGGTG
GTCATGCTGACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCGTCCGGCTTCCTGGTCAAGGA
CACCGAGCCGGAGGAACTGCTGCGCGCCGTACGGGCGGTGGTCGCCGGAGACGCGCTGCTCTCACCCGGGGTGACGCGCC
GCCTGATCGGCGAGTTCGCGGCCCGCTCCAAGGCCCCGGAGGCGGCGGCGGAGCTGGAGCGGCTGACCGAGCGGGAGCGC
GAGGTGATGGCCCTGGTCGGGATGGGCCTGTCCAACGAGGAGATCGCCCGCCGGCTCGTGGTCAGTCCGCTGACCGCGAA
GACGCACGTCAGCCGCGCCATGATCAAGCTGGGTGCCCGCGACCGGGCCCAGCTGGTGGTGCTCGCCTACGAGTCGGGGC
TGGTCCGGCCCGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38