Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG386_RS14460 Genome accession   NZ_CP108067
Coordinates   3472323..3472991 (+) Length   222 a.a.
NCBI ID   WP_328788519.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00273     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3467323..3477991
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG386_RS14440 (OG386_14440) - 3468603..3469301 (-) 699 WP_328788516.1 DUF4190 domain-containing protein -
  OG386_RS14445 (OG386_14445) - 3469412..3470437 (+) 1026 WP_328788517.1 adenosine deaminase -
  OG386_RS14450 (OG386_14450) - 3470474..3471163 (+) 690 WP_328788518.1 glycerophosphodiester phosphodiesterase -
  OG386_RS14455 (OG386_14455) - 3471250..3472326 (+) 1077 WP_328793253.1 histidine kinase -
  OG386_RS14460 (OG386_14460) vraR 3472323..3472991 (+) 669 WP_328788519.1 response regulator transcription factor Regulator
  OG386_RS14465 (OG386_14465) - 3473142..3474341 (+) 1200 WP_328788520.1 serine hydrolase domain-containing protein -
  OG386_RS14470 (OG386_14470) - 3474345..3474809 (-) 465 WP_328788521.1 hypothetical protein -
  OG386_RS14475 (OG386_14475) - 3474889..3476067 (-) 1179 WP_328793254.1 spermidine/putrescine ABC transporter substrate-binding protein -
  OG386_RS14480 (OG386_14480) - 3476160..3477599 (-) 1440 WP_328788522.1 gamma-aminobutyraldehyde dehydrogenase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23597.04 Da        Isoelectric Point: 4.5880

>NTDB_id=652458 OG386_RS14460 WP_328788519.1 3472323..3472991(+) (vraR) [Streptomyces sp. NBC_00273]
MTIRVVVADDQELVRSGFAMILDVQEDIEVVAEVGDGAAAVEAVARLAPDVALLDIRMPVLDGIEACRAISTGSACRTVM
LTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVRVVAAGESLLAPSVARRLIEEYTTATVRPALPADRLEVLTARERE
TLLHLGRGLSNAEIAASLVVSEHTVKSHVGNVLAKLGLRDRIQAVICAYETGLIAAGTPSGE

Nucleotide


Download         Length: 669 bp        

>NTDB_id=652458 OG386_RS14460 WP_328788519.1 3472323..3472991(+) (vraR) [Streptomyces sp. NBC_00273]
TTGACGATCCGTGTGGTGGTGGCCGATGACCAGGAGCTGGTGCGCAGCGGCTTCGCGATGATCCTGGACGTCCAGGAGGA
CATCGAGGTCGTGGCGGAGGTGGGGGACGGCGCGGCGGCGGTGGAGGCGGTGGCCCGGCTCGCGCCGGACGTGGCGCTGC
TGGACATCCGGATGCCGGTGCTGGACGGGATCGAGGCCTGCCGGGCGATTTCGACCGGGAGCGCGTGCCGCACGGTGATG
CTCACGACCTTCGATTCGGACGAGTACGTGTACGAGGCGCTGCACGCGGGGGCGAGCGGGTTCCTGCTGAAGGACGTGCG
GCGGGACGACCTGGTGCACGCGGTGCGGGTGGTGGCGGCGGGCGAGTCGCTGCTGGCGCCGTCGGTGGCGCGGCGGCTGA
TCGAGGAGTACACGACGGCGACGGTGCGGCCCGCCCTTCCGGCGGACCGGCTGGAGGTGCTGACGGCGCGGGAACGGGAG
ACGCTGCTGCACCTGGGGCGGGGCCTGTCCAACGCGGAGATCGCGGCGTCGCTGGTGGTGAGCGAGCACACCGTGAAGTC
GCACGTGGGGAACGTGCTGGCGAAGCTGGGGCTGCGGGACCGGATCCAGGCGGTGATCTGCGCGTACGAGACGGGCCTGA
TCGCGGCGGGTACTCCCTCTGGGGAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.284

98.198

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

100

0.396