Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG386_RS06170 Genome accession   NZ_CP108067
Coordinates   1449528..1450214 (-) Length   228 a.a.
NCBI ID   WP_328787142.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00273     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1444528..1455214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG386_RS06145 (OG386_06125) - 1444990..1445754 (-) 765 WP_328787137.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG386_RS06150 (OG386_06130) - 1446361..1446993 (-) 633 WP_328787138.1 GNAT family N-acetyltransferase -
  OG386_RS06155 (OG386_06135) - 1447079..1447513 (-) 435 WP_328787139.1 VOC family protein -
  OG386_RS06160 (OG386_06140) - 1447594..1448550 (-) 957 WP_328787140.1 tellurite resistance/C4-dicarboxylate transporter family protein -
  OG386_RS06165 (OG386_06145) - 1449000..1449455 (+) 456 WP_328787141.1 DoxX family protein -
  OG386_RS06170 (OG386_06150) vraR 1449528..1450214 (-) 687 WP_328787142.1 response regulator transcription factor Regulator
  OG386_RS06175 (OG386_06155) - 1450211..1451437 (-) 1227 WP_328787143.1 sensor histidine kinase -
  OG386_RS06180 (OG386_06160) - 1451570..1452502 (+) 933 WP_328787144.1 ATP-binding cassette domain-containing protein -
  OG386_RS06185 (OG386_06165) - 1452512..1453090 (+) 579 WP_328787145.1 YdeI/OmpD-associated family protein -
  OG386_RS06190 (OG386_06170) - 1453213..1453617 (-) 405 WP_328787146.1 DUF5997 family protein -
  OG386_RS06195 (OG386_06175) - 1453676..1454497 (+) 822 WP_328787147.1 LysR substrate-binding domain-containing protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 23852.65 Da        Isoelectric Point: 4.7242

>NTDB_id=652445 OG386_RS06170 WP_328787142.1 1449528..1450214(-) (vraR) [Streptomyces sp. NBC_00273]
MTAAPARAIRVLLVDDQPLVRSGLRVLMADTADLEVVGEAGTGTDGVRLAAELRPDVVVMDIRMPGMDGIEATGLITTAA
EAVKVLVLTTFDEDDHVYGALRAGASGFAVKDMAVEDILAAIRVIAAGDALIAPGVTRRLIADFVRAPGPAAPEVRAPRP
VAGITEREREVLTLVGLGLSNGEIAEELFISAATAKSHVSRLFTKLGARDRVQLVITAYEIGLVAAPR

Nucleotide


Download         Length: 687 bp        

>NTDB_id=652445 OG386_RS06170 WP_328787142.1 1449528..1450214(-) (vraR) [Streptomyces sp. NBC_00273]
ATGACCGCCGCTCCCGCGCGGGCGATCCGCGTCCTGCTCGTGGACGACCAGCCGTTGGTCAGGTCCGGTCTGCGGGTGCT
GATGGCCGACACCGCCGACCTGGAGGTCGTCGGCGAGGCCGGTACGGGTACCGACGGCGTCCGCCTCGCCGCCGAACTGC
GCCCCGACGTGGTGGTGATGGACATCCGGATGCCGGGCATGGACGGCATCGAGGCCACCGGGCTGATCACCACGGCCGCG
GAGGCCGTCAAGGTGCTCGTGCTGACCACCTTCGACGAGGACGACCACGTCTACGGGGCGCTGCGCGCCGGCGCGAGCGG
GTTCGCCGTGAAGGACATGGCCGTGGAGGACATCCTCGCCGCGATCCGGGTGATCGCCGCGGGGGACGCCCTGATCGCGC
CGGGCGTCACCCGCCGGCTGATCGCGGACTTCGTCCGCGCGCCCGGGCCGGCGGCGCCCGAGGTGCGGGCGCCGCGACCC
GTCGCGGGGATCACCGAGCGCGAGCGGGAGGTGCTGACCTTGGTGGGGCTGGGTCTCTCGAACGGCGAGATAGCCGAGGA
GCTGTTCATCTCGGCGGCCACGGCCAAATCGCACGTCTCGCGCCTGTTCACCAAGCTCGGCGCCCGGGACCGGGTCCAAC
TCGTCATCACGGCCTACGAGATAGGGCTGGTCGCAGCGCCCCGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(165-218)

Response regulator receiver domain (Response_reg)

(11-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.426

94.737

0.364