Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS25425 Genome accession   NZ_CP108055
Coordinates   5528864..5529520 (-) Length   218 a.a.
NCBI ID   WP_328748797.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5523864..5534520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS25405 (OHT57_25425) - 5524493..5525035 (+) 543 WP_328748793.1 bacterial proteasome activator family protein -
  OHT57_RS25410 (OHT57_25430) - 5525548..5527113 (+) 1566 WP_328748794.1 protein kinase -
  OHT57_RS25415 (OHT57_25435) - 5527189..5528256 (-) 1068 WP_328748795.1 phosphotransferase -
  OHT57_RS25420 (OHT57_25440) - 5528379..5528804 (-) 426 WP_328748796.1 pyridoxamine 5'-phosphate oxidase family protein -
  OHT57_RS25425 (OHT57_25445) vraR 5528864..5529520 (-) 657 WP_328748797.1 response regulator transcription factor Regulator
  OHT57_RS25430 (OHT57_25450) pdhA 5529873..5531021 (+) 1149 WP_328748798.1 pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha -
  OHT57_RS25435 (OHT57_25455) - 5531024..5532019 (+) 996 WP_328748799.1 alpha-ketoacid dehydrogenase subunit beta -
  OHT57_RS25440 (OHT57_25460) - 5532030..5533418 (+) 1389 WP_328748800.1 dihydrolipoamide acetyltransferase family protein -
  OHT57_RS25445 (OHT57_25465) - 5533507..5534466 (-) 960 WP_328748801.1 Bro-N domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23857.22 Da        Isoelectric Point: 6.3515

>NTDB_id=652289 OHT57_RS25425 WP_328748797.1 5528864..5529520(-) (vraR) [Streptomyces sp. NBC_00285]
MRENGKIRVFLVDDHEVVRRGVHELLSVEDDIEVVGEAGTAAEALARIPATRPDVAVLDVRLPDGSGVEVCREIRSRDDS
VKCLMLTSFADDEALFDAIMAGASGYALKAIRGAELLDAVRGVAAGRSLLDPVATARVLERLRDGGAKQDDRLAHLTDQE
RRILDLVGEGLTNRQIGERLHLAEKTIKNYVSSLLSKLGMQRRSQAAAYVARLQVQRH

Nucleotide


Download         Length: 657 bp        

>NTDB_id=652289 OHT57_RS25425 WP_328748797.1 5528864..5529520(-) (vraR) [Streptomyces sp. NBC_00285]
GTGCGCGAAAACGGAAAAATCAGGGTATTTCTTGTCGACGACCATGAGGTGGTCCGGCGGGGTGTCCATGAACTCCTCTC
GGTGGAGGACGACATCGAGGTGGTCGGCGAGGCCGGCACGGCGGCCGAAGCTCTGGCGCGGATTCCGGCCACCCGGCCCG
ACGTGGCGGTGCTCGACGTACGACTCCCCGACGGCAGCGGGGTCGAGGTGTGCCGGGAGATCCGCTCGCGGGACGACTCC
GTGAAGTGCCTGATGCTGACCTCGTTCGCCGATGACGAGGCTCTTTTCGACGCGATCATGGCCGGGGCATCCGGTTACGC
CCTGAAGGCCATCCGTGGCGCCGAACTGCTGGATGCGGTCCGGGGCGTGGCCGCCGGCAGGTCCCTGCTGGATCCGGTGG
CCACCGCGCGCGTCCTGGAGCGGCTGCGGGACGGCGGCGCCAAACAGGACGACCGGCTCGCGCACCTCACCGACCAGGAG
CGCAGAATCCTCGATCTGGTGGGCGAAGGTCTCACCAACCGCCAGATCGGCGAGCGGCTGCACCTCGCCGAGAAGACGAT
CAAGAACTATGTGTCGAGTCTGCTTTCCAAACTCGGCATGCAAAGACGTTCCCAGGCCGCCGCGTACGTGGCTCGCCTGC
AGGTGCAGCGGCATTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(9-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.916

93.119

0.362