Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT57_RS05380 Genome accession   NZ_CP108055
Coordinates   1119917..1120564 (+) Length   215 a.a.
NCBI ID   WP_328744877.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00285     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1114917..1125564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT57_RS05355 (OHT57_05380) - 1115714..1116826 (-) 1113 WP_328744872.1 Gfo/Idh/MocA family oxidoreductase -
  OHT57_RS05360 (OHT57_05385) - 1117002..1117370 (-) 369 WP_328744873.1 hypothetical protein -
  OHT57_RS05365 (OHT57_05390) - 1117421..1117801 (+) 381 WP_328744874.1 hypothetical protein -
  OHT57_RS05370 (OHT57_05395) - 1117767..1118555 (-) 789 WP_328744875.1 class I SAM-dependent methyltransferase -
  OHT57_RS05375 (OHT57_05400) - 1118715..1119920 (+) 1206 WP_328744876.1 sensor histidine kinase -
  OHT57_RS05380 (OHT57_05405) vraR 1119917..1120564 (+) 648 WP_328744877.1 response regulator transcription factor Regulator
  OHT57_RS05385 (OHT57_05410) - 1120725..1121864 (+) 1140 WP_328744878.1 GNAT family N-acetyltransferase -
  OHT57_RS05390 (OHT57_05415) - 1122051..1123280 (+) 1230 WP_328744879.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
  OHT57_RS05395 (OHT57_05420) - 1123357..1124808 (+) 1452 WP_328744880.1 glyceraldehyde-3-phosphate dehydrogenase -
  OHT57_RS05400 (OHT57_05425) - 1124747..1124941 (-) 195 Protein_1077 hypothetical protein -
  OHT57_RS05405 (OHT57_05430) - 1125047..1125244 (-) 198 WP_328744881.1 hypothetical protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 22488.86 Da        Isoelectric Point: 6.3419

>NTDB_id=652245 OHT57_RS05380 WP_328744877.1 1119917..1120564(+) (vraR) [Streptomyces sp. NBC_00285]
MSTSPPTSPVRLLLCDDHAVVRAGLRALLSSAGGIDVVGEAATGEEALAMAAHLNPDVVLMDLQLDGGMDGVTATRALTA
GGAHGPRVLVLTMFDTDADITRAIEAGATGYLLKAEQPEELFTAIREAATGRGTLSAPVADRLLTRLRSPRPDLSAREHD
ILAQLALGLGNREIARALFISEATVKTHLGRIYVKLGVETRAGAVAVAKERRLLG

Nucleotide


Download         Length: 648 bp        

>NTDB_id=652245 OHT57_RS05380 WP_328744877.1 1119917..1120564(+) (vraR) [Streptomyces sp. NBC_00285]
GTGAGTACGTCCCCGCCCACCTCCCCCGTCCGGCTTCTGCTCTGCGACGACCATGCCGTCGTCCGTGCCGGTCTGCGCGC
CCTGCTCTCCAGCGCCGGGGGCATCGACGTCGTCGGGGAGGCGGCCACCGGCGAGGAGGCGCTCGCCATGGCGGCCCATC
TGAACCCCGACGTCGTACTGATGGATCTTCAACTCGACGGCGGGATGGACGGGGTGACGGCCACCCGGGCACTGACCGCC
GGCGGCGCGCACGGCCCTCGTGTCCTGGTGCTGACCATGTTCGACACCGACGCCGACATCACCCGGGCCATCGAGGCGGG
CGCAACCGGCTATCTCCTGAAGGCCGAACAGCCCGAGGAGTTGTTCACGGCGATCCGCGAGGCCGCGACCGGCCGCGGCA
CGCTCTCCGCCCCGGTGGCCGACCGGCTGCTGACCCGGCTGCGCAGCCCGCGTCCGGACCTGTCCGCACGCGAGCACGAC
ATCCTCGCGCAGCTCGCCCTCGGCCTCGGCAACCGGGAGATCGCCCGCGCCCTGTTCATCAGCGAGGCGACCGTCAAAAC
CCATCTGGGGCGCATCTACGTCAAGTTGGGCGTGGAGACCCGGGCGGGCGCGGTGGCGGTCGCCAAGGAACGACGGCTGC
TGGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-208)

Response regulator receiver domain (Response_reg)

(13-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.799

97.209

0.367