Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG985_RS39435 Genome accession   NZ_CP108046
Coordinates   8713780..8714445 (+) Length   221 a.a.
NCBI ID   WP_371673173.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00289     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8708780..8719445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG985_RS39415 (OG985_39305) - 8709876..8711123 (+) 1248 WP_371673169.1 geranylgeranyl reductase family protein -
  OG985_RS39420 (OG985_39310) - 8711113..8711562 (-) 450 WP_371673170.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OG985_RS39425 (OG985_39315) - 8711708..8712436 (+) 729 WP_371673171.1 TetR/AcrR family transcriptional regulator -
  OG985_RS39430 (OG985_39320) - 8712548..8713783 (+) 1236 WP_371673172.1 sensor histidine kinase -
  OG985_RS39435 (OG985_39325) vraR 8713780..8714445 (+) 666 WP_371673173.1 response regulator Regulator
  OG985_RS39440 (OG985_39330) - 8714406..8714690 (-) 285 WP_371673174.1 DUF6332 family protein -
  OG985_RS39445 (OG985_39335) - 8714899..8716392 (-) 1494 WP_371673175.1 MFS transporter -
  OG985_RS39450 (OG985_39340) - 8716478..8716870 (+) 393 WP_371673176.1 MarR family winged helix-turn-helix transcriptional regulator -
  OG985_RS39455 (OG985_39345) - 8717046..8717786 (-) 741 WP_371673177.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG985_RS39460 (OG985_39350) - 8717870..8719129 (-) 1260 WP_371673178.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23652.39 Da        Isoelectric Point: 4.8780

>NTDB_id=652041 OG985_RS39435 WP_371673173.1 8713780..8714445(+) (vraR) [Streptomyces sp. NBC_00289]
MIRVLLADDQSLVRAGFRALLDAQPDIEVAGEAADGEEALGKARELRPDVVLMDIRMPVLDGLAATRHISADGGLADVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAAADALAGLTERER
EVMALVGIGLSNMEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=652041 OG985_RS39435 WP_371673173.1 8713780..8714445(+) (vraR) [Streptomyces sp. NBC_00289]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCACTGGTACGGGCCGGCTTCCGGGCGCTGCTCGACGCGCAGCCGGACAT
CGAGGTGGCCGGTGAGGCCGCGGACGGCGAGGAGGCGCTTGGCAAGGCGCGCGAACTGCGCCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCGTGCTCGACGGCCTGGCCGCGACCCGCCACATCTCGGCCGACGGTGGGCTGGCGGACGTCAAGGTG
GTCATGCTGACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCGGGCGCCTCGGGCTTCCTGGTGAAGGA
CACCGAGCCGGAAGAACTCCTGCGCGCGGTCAGGGCGGTGGTCGGGGGCGACGCGCTGCTGTCACCGGGAGTGACCCGCC
GTCTGATCGCCGAGTTCGCGGCCCGTTCGAAGGAGCCCGCCGCCGCCGACGCCCTCGCCGGGCTGACCGAGCGGGAGCGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTGTCCAACATGGAGATCGCCCGCCGCCTGGTGGTCAGCCCACTCACCGCGAA
GACACACGTGAGCCGCACCATGGTGAAGCTGGGCGCCCGTGACCGGGCCCAACTGGTGGTGCTGGCCTACGAGTCGGGGT
TGGTGCGCCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38