Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG985_RS12450 Genome accession   NZ_CP108046
Coordinates   2669772..2670452 (-) Length   226 a.a.
NCBI ID   WP_371668366.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00289     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2664772..2675452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG985_RS12430 (OG985_12305) - 2665438..2666019 (-) 582 WP_371668363.1 sugar kinase -
  OG985_RS12435 (OG985_12310) - 2666016..2667164 (-) 1149 WP_371668364.1 ROK family glucokinase -
  OG985_RS12440 (OG985_12315) - 2667638..2668375 (-) 738 WP_371674346.1 GntR family transcriptional regulator -
  OG985_RS12445 (OG985_12320) - 2668505..2669506 (+) 1002 WP_371668365.1 Gfo/Idh/MocA family oxidoreductase -
  OG985_RS12450 (OG985_12325) vraR 2669772..2670452 (-) 681 WP_371668366.1 response regulator Regulator
  OG985_RS12455 (OG985_12330) - 2670538..2671794 (-) 1257 WP_371674347.1 sensor histidine kinase -
  OG985_RS12460 (OG985_12335) - 2672001..2672201 (+) 201 WP_371668367.1 hypothetical protein -
  OG985_RS12465 (OG985_12340) - 2672264..2672659 (-) 396 WP_371668368.1 ribonuclease domain-containing protein -
  OG985_RS12470 (OG985_12345) - 2672745..2673650 (-) 906 WP_371674348.1 DMT family transporter -
  OG985_RS12475 (OG985_12350) - 2673855..2674673 (-) 819 WP_371668369.1 AIM24 family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24156.75 Da        Isoelectric Point: 5.0027

>NTDB_id=651978 OG985_RS12450 WP_371668366.1 2669772..2670452(-) (vraR) [Streptomyces sp. NBC_00289]
MTAIRLLLVDDDPLVRAGLSLMLGGAEDIEIVGEAADGAEVEALVDRTRPDVVLMDIRMPSVDGLTATERLRRRPDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTRPAEILAAVRRVAAGEPVLSPTVTRRLMDHAAGTTADTRRARARDRIALLND
RETEVAVAVGRGLANAEIAGALFMSVATVKTHVSRVLAKLDLNNRVQIALLTYDAGLLEEAEGDTA

Nucleotide


Download         Length: 681 bp        

>NTDB_id=651978 OG985_RS12450 WP_371668366.1 2669772..2670452(-) (vraR) [Streptomyces sp. NBC_00289]
ATGACTGCGATCAGACTGCTCCTCGTCGACGACGACCCGCTGGTGAGGGCCGGACTCTCCCTGATGCTGGGCGGCGCCGA
GGACATCGAGATCGTCGGCGAGGCGGCCGACGGCGCCGAGGTCGAGGCACTGGTCGACCGCACCCGCCCCGACGTCGTCC
TCATGGACATCCGGATGCCGTCGGTGGACGGCCTCACCGCCACCGAGCGGCTGCGACGCCGGCCGGACGCCCCGCAGGTC
GTGGTCCTCACCACCTTCCACGCGGACGAGCAGGTGCTGCGGGCGCTGCGCGCGGGCGCCGCCGGGTTCGTCCTCAAGGA
CACCCGGCCCGCCGAGATCCTCGCCGCGGTGCGCAGGGTCGCGGCGGGCGAGCCCGTCCTGTCGCCGACCGTCACCCGCC
GCCTGATGGACCACGCGGCCGGTACCACCGCCGACACCCGCCGCGCGCGTGCGCGGGACCGCATCGCCCTTCTGAACGAC
CGCGAGACCGAGGTCGCCGTCGCGGTCGGCCGGGGCCTCGCCAACGCGGAGATCGCCGGCGCGCTCTTCATGAGCGTCGC
CACCGTCAAGACCCACGTCTCGCGCGTCCTGGCCAAGCTCGACCTCAACAACCGCGTGCAGATCGCCCTGTTGACGTACG
ACGCGGGACTGCTGGAGGAAGCCGAAGGAGACACGGCGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.104

97.788

0.363