Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB47_RS22535 Genome accession   NZ_CP108030
Coordinates   4985566..4986231 (-) Length   221 a.a.
NCBI ID   WP_266711607.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00311     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4980566..4991231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB47_RS22510 (OHB47_22540) - 4980922..4981428 (-) 507 WP_327662690.1 MarR family transcriptional regulator -
  OHB47_RS22515 (OHB47_22545) - 4981521..4982453 (+) 933 WP_327670853.1 ABC transporter ATP-binding protein -
  OHB47_RS22520 (OHB47_22550) - 4982450..4984060 (+) 1611 WP_327670854.1 ABC transporter permease -
  OHB47_RS22525 (OHB47_22555) - 4984106..4984354 (+) 249 WP_327670856.1 hypothetical protein -
  OHB47_RS22530 (OHB47_22560) - 4984317..4985546 (-) 1230 WP_327670857.1 cytochrome P450 -
  OHB47_RS22535 (OHB47_22565) vraR 4985566..4986231 (-) 666 WP_266711607.1 response regulator transcription factor Regulator
  OHB47_RS22540 (OHB47_22570) - 4986228..4987562 (-) 1335 WP_327670858.1 histidine kinase -
  OHB47_RS22545 (OHB47_22575) - 4987660..4988550 (-) 891 WP_327670859.1 alpha/beta hydrolase -
  OHB47_RS22550 (OHB47_22580) - 4988678..4989310 (+) 633 WP_327670860.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24042.80 Da        Isoelectric Point: 4.6799

>NTDB_id=651673 OHB47_RS22535 WP_266711607.1 4985566..4986231(-) (vraR) [Streptomyces sp. NBC_00311]
MIRVLVADDQMMVREGFSVLLNAMPDFEVVGEAVNGVEAIAKVRELRPDVVLMDIRMPELNGIEATREIVAADAGTKVLV
LTTFDLDEYVYQALRAGASGFLLKDASARELADGVRVVASGEALLAPTVTRRLITEFAKLSETSRFPVGRQTGAYGELTE
RETEVLVLIAQGLSNIEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=651673 OHB47_RS22535 WP_266711607.1 4985566..4986231(-) (vraR) [Streptomyces sp. NBC_00311]
GTGATCAGGGTGCTGGTCGCCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTATTGAACGCCATGCCGGACTT
CGAGGTCGTCGGCGAGGCGGTCAACGGCGTGGAGGCCATCGCCAAGGTCCGCGAACTCCGCCCCGACGTCGTCCTGATGG
ACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGCGAGATCGTCGCGGCGGACGCGGGCACGAAGGTGCTCGTC
CTGACCACCTTCGACCTGGACGAGTACGTGTACCAGGCGCTGCGGGCCGGGGCCTCCGGCTTCCTCCTCAAGGACGCCTC
CGCGCGCGAACTCGCCGACGGAGTACGGGTGGTGGCGAGCGGCGAGGCCCTCCTCGCGCCGACTGTGACCCGCCGCCTGA
TCACCGAGTTCGCCAAGCTGTCCGAGACGTCGAGGTTCCCCGTGGGGCGGCAGACGGGCGCGTACGGGGAGCTGACCGAG
CGCGAGACGGAGGTGCTCGTCCTGATCGCGCAGGGCCTGTCGAACATCGAGATCGCCGAGCGGCTCGTGGTCGCCGAGTC
GACGATCAAGACGCATGTGAGCCGGGTCCTGGTGAAGCTGGGGCTGCGCGACCGGACGCAGGCGGCGGTGTTCGCGTACG
AGGCACGTCTGGTCACGCCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.24

98.19

0.434
  degU Bacillus subtilis subsp. subtilis str. 168

43.119

98.643

0.425