Detailed information NTG0065167

Bioinformatically predicted

Overview

• Name: amiD
• Type: Regulator
• Locus tag: SPYJRS4_RS01325
• Genome accession: NZ_AP012335
• Coordinates: 253434..254360 (+)
• Length: 308 a.a.
• NCBI ID: WP_002986004.1
• Uniprot ID: Q1JNF8
• Organism: Streptococcus pyogenes JRS4
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 248434..259360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYJRS4_RS01315 (SPYJRS4_0244)	amiA	249897..251867 (+)	1971	WP_047149475.1	peptide ABC transporter substrate-binding protein	Regulator
SPYJRS4_RS01320 (SPYJRS4_0245)	amiC	251932..253434 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
SPYJRS4_RS01325 (SPYJRS4_0246)	amiD	253434..254360 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
SPYJRS4_RS01330 (SPYJRS4_0247)	amiE	254369..255439 (+)	1071	WP_010921893.1	ABC transporter ATP-binding protein	Regulator
SPYJRS4_RS01335 (SPYJRS4_0248)	amiF	255432..256355 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator

Sequence

Protein

• Length: 308 a.a.
• Molecular weight: 34862.81 Da
• Isoelectric Point: 8.5670

>NTDB_id=65167 SPYJRS4_RS01325 WP_002986004.1 253434..254360(+) (amiD) [Streptococcus pyogenes JRS4]
MESIDKSKFRFVERDSEASEVIDTPAYSYWKSVFRQFFSKKSTVFMLVILVTVLMMSFIYPMFANYDFNDVSNINDFSKR
YIWPNAEYWFGTDKNGQSLFDGVWYGARNSILISVIATLINITIGVVLGAIWGVSKAFDKVMIEIYNIISNIPSMLIIIV
LTYSLGAGFWNLILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKNLLPQLVSVIMTMLSQMLPVYVS
SEAFLSFFGIGLPTTTPSLGRLIANYSSNLTTNAYLFWIPLVTLILVSLPLYIVGQNLADASDPRSHR

Nucleotide

• Length: 927 bp

>NTDB_id=65167 SPYJRS4_RS01325 WP_002986004.1 253434..254360(+) (amiD) [Streptococcus pyogenes JRS4]
ATGGAATCGATTGATAAATCTAAATTTCGATTTGTTGAGCGCGATAGTGAAGCCTCCGAAGTGATTGATACCCCTGCTTA
TTCTTACTGGAAATCAGTGTTTCGTCAGTTTTTTTCTAAAAAATCTACAGTCTTTATGCTCGTGATTTTAGTGACAGTCT
TGATGATGAGCTTTATTTATCCAATGTTTGCCAACTACGACTTTAATGACGTTAGTAATATCAATGACTTTTCAAAGCGT
TATATTTGGCCAAATGCAGAGTACTGGTTTGGAACCGACAAAAATGGGCAATCTCTGTTTGATGGTGTTTGGTATGGGGC
ACGTAATTCTATTTTAATCTCAGTTATAGCGACACTAATTAATATCACCATTGGGGTAGTGTTAGGAGCCATATGGGGAG
TTTCTAAAGCATTTGATAAAGTTATGATTGAAATTTATAACATTATCTCAAATATCCCTTCTATGCTTATTATCATTGTT
TTGACCTATTCATTAGGTGCAGGATTTTGGAATTTGATTCTAGCTTTCTGTATCACTGGATGGATTGGTGTCGCCTACTC
CATCCGTGTTCAAATCTTGCGTTACCGTGATTTAGAATACAACCTTGCTAGTCAAACTTTGGGAACACCAATGTACAAGA
TTGCTGTTAAGAACCTGCTGCCTCAATTGGTTTCAGTTATCATGACTATGTTGTCACAAATGCTACCAGTTTATGTATCT
TCTGAGGCCTTCTTATCCTTCTTTGGGATTGGTTTACCAACCACCACTCCAAGTTTAGGACGTTTGATTGCTAATTATTC
AAGCAACTTAACAACAAATGCCTACCTCTTTTGGATTCCCTTAGTAACATTGATTTTAGTATCGTTACCACTATACATTG
TCGGACAAAACTTGGCTGATGCCAGTGACCCACGTTCACATAGATAG

Domains

Predicted by InterproScan.

• N-terminal TM domain of oligopeptide transport permease C (OppC_N) (28-72)

• Binding-protein-dependent transport system inner membrane component (BPD_transp_1) (125-305)

3D structure

• AlphaFold DB: Q1JNF8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiD	Streptococcus salivarius strain HSISS4	73.701	100	0.737
amiD	Streptococcus thermophilus LMG 18311	73.052	100	0.731
amiD	Streptococcus thermophilus LMD-9	73.052	100	0.731