Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG878_RS18950 Genome accession   NZ_CP108023
Coordinates   4257883..4258545 (-) Length   220 a.a.
NCBI ID   WP_328887884.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00316     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4252883..4263545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG878_RS18930 (OG878_18965) - 4253186..4253728 (-) 543 WP_328887880.1 MarR family transcriptional regulator -
  OG878_RS18935 (OG878_18970) - 4253840..4254760 (+) 921 WP_328887881.1 ABC transporter ATP-binding protein -
  OG878_RS18940 (OG878_18975) - 4254757..4256361 (+) 1605 WP_328887882.1 ABC transporter permease -
  OG878_RS18945 (OG878_18980) - 4256611..4257837 (-) 1227 WP_328887883.1 cytochrome P450 -
  OG878_RS18950 (OG878_18985) vraR 4257883..4258545 (-) 663 WP_328887884.1 response regulator transcription factor Regulator
  OG878_RS18955 (OG878_18990) - 4258542..4259873 (-) 1332 WP_328887885.1 histidine kinase -
  OG878_RS18960 (OG878_18995) - 4260006..4260881 (-) 876 WP_328887886.1 alpha/beta hydrolase -
  OG878_RS18965 (OG878_19000) kynU 4261171..4262370 (-) 1200 WP_328887887.1 kynureninase -
  OG878_RS18970 (OG878_19005) - 4262363..4263211 (-) 849 WP_328887888.1 tryptophan 2,3-dioxygenase family protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23480.27 Da        Isoelectric Point: 4.9350

>NTDB_id=651591 OG878_RS18950 WP_328887884.1 4257883..4258545(-) (vraR) [Streptomyces sp. NBC_00316]
MNDIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGRQAIAQAAALRPDVVLMDIRMPELNGIEATREIVAADAAAKV
LVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTKRLITEFSRLAGAPRPPALARIGDLTER
ETEVLVLIAQGLSNAEIASHLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=651591 OG878_RS18950 WP_328887884.1 4257883..4258545(-) (vraR) [Streptomyces sp. NBC_00316]
ATGAACGACATCCGGGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGTTTCTCGGTGCTCCTGGGGGCGATGCC
GGGCATCGAGGTCGTCGGCGAGGCCGTCGACGGCCGGCAGGCCATCGCCCAGGCCGCCGCCCTGCGGCCCGACGTGGTGC
TGATGGACATCCGGATGCCGGAGCTCAACGGCATCGAGGCGACCCGCGAGATCGTCGCCGCCGACGCGGCCGCCAAGGTG
CTCGTGCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCCGGGGCGTCCGGATTCCTGCTGAAGGA
CGCCTCTGCCCGCCAGCTCGCCGACGGGGTACGGGTCGTGGCGTCCGGGGAGGCGTTGCTGGCACCCACGGTCACCAAGC
GGCTGATCACCGAGTTCTCCCGGCTCGCCGGGGCCCCGCGGCCGCCCGCGCTCGCCCGGATCGGCGATCTGACGGAGCGC
GAGACGGAGGTGCTCGTGCTCATCGCGCAGGGCCTGTCCAACGCGGAGATCGCCTCGCATCTGGTGGTCGCCGAATCCAC
CATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGGGACCGCACCCAGGCGGCGGTGTTCGCGTACGAGG
CGCGGCTGGTCACGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory proteins, luxR family (GerE)

(157-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.393

97.273

0.432
  degU Bacillus subtilis subsp. subtilis str. 168

42.727

100

0.427