Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB16_RS35805 Genome accession   NZ_CP108008
Coordinates   7851915..7852598 (-) Length   227 a.a.
NCBI ID   WP_271417078.1    Uniprot ID   A0ABV9WNE9
Organism   Streptomyces sp. NBC_00334     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7846915..7857598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB16_RS35770 (OHB16_35770) - 7847043..7847474 (-) 432 WP_328661222.1 hypothetical protein -
  OHB16_RS35775 (OHB16_35775) - 7847894..7848040 (-) 147 WP_328661223.1 hypothetical protein -
  OHB16_RS35780 (OHB16_35780) - 7847981..7848466 (+) 486 Protein_7066 NmrA family NAD(P)-binding protein -
  OHB16_RS35785 (OHB16_35785) - 7848792..7848974 (+) 183 WP_271417283.1 hypothetical protein -
  OHB16_RS35790 - 7849091..7849330 (-) 240 Protein_7068 helix-turn-helix domain-containing protein -
  OHB16_RS35795 (OHB16_35795) - 7849308..7850222 (+) 915 WP_328661226.1 IS5 family transposase -
  OHB16_RS35800 (OHB16_35800) - 7850283..7851395 (-) 1113 WP_328661228.1 ABC transporter substrate-binding protein -
  OHB16_RS35805 (OHB16_35805) vraR 7851915..7852598 (-) 684 WP_271417078.1 response regulator transcription factor Regulator
  OHB16_RS35810 (OHB16_35810) - 7852604..7853806 (-) 1203 WP_271413817.1 sensor histidine kinase -
  OHB16_RS35815 (OHB16_35815) - 7854009..7855082 (+) 1074 WP_271417079.1 glycosyltransferase 87 family protein -
  OHB16_RS35820 (OHB16_35820) - 7855079..7856242 (+) 1164 WP_328661231.1 glycosyltransferase family 4 protein -
  OHB16_RS35825 (OHB16_35825) - 7856239..7856379 (+) 141 Protein_7075 IS5/IS1182 family transposase -
  OHB16_RS35830 (OHB16_35830) - 7857148..7857369 (+) 222 WP_271413819.1 hypothetical protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24555.43 Da        Isoelectric Point: 6.6562

>NTDB_id=651394 OHB16_RS35805 WP_271417078.1 7851915..7852598(-) (vraR) [Streptomyces sp. NBC_00334]
MKKELGVIRALVADDQAVVRTGFMNLLNTQEDIEVVGEAEDGVQAVRIAAETRPDLALLDIRMPHKNGIEAAREILAASG
GTTKVLMLTTFGLDEYVYDALAAGAGGFLLKDATFPELLHAVRVVAAGNALLSPEITKRLIGAFVRARTERLPVHSVGEL
TAREAEVLTLIARGLSNTEIASRLTITDHTVKTHINRLFAKLKLRDRAQAVIVAYELGLVRVEGRAD

Nucleotide


Download         Length: 684 bp        

>NTDB_id=651394 OHB16_RS35805 WP_271417078.1 7851915..7852598(-) (vraR) [Streptomyces sp. NBC_00334]
ATGAAGAAGGAGTTGGGTGTGATCAGGGCACTGGTCGCTGACGATCAGGCGGTCGTCCGCACCGGCTTTATGAACCTCCT
CAACACTCAGGAGGACATCGAGGTCGTGGGCGAGGCGGAGGACGGTGTGCAGGCGGTGCGCATCGCCGCCGAGACCCGGC
CCGACCTCGCGCTCCTCGATATCCGGATGCCGCACAAGAACGGCATCGAAGCAGCCCGCGAGATTCTGGCCGCCTCCGGG
GGCACGACGAAGGTCCTGATGCTGACGACCTTCGGGCTCGACGAGTACGTGTACGACGCGCTCGCGGCCGGCGCGGGCGG
CTTTCTGCTCAAGGACGCCACCTTTCCCGAACTACTGCACGCGGTGCGAGTAGTGGCGGCCGGGAACGCGCTGCTCTCGC
CCGAGATAACCAAGCGGTTGATCGGCGCGTTCGTGCGTGCGCGGACCGAGCGACTGCCGGTTCACTCCGTGGGGGAGCTC
ACGGCGCGTGAGGCGGAGGTGCTTACGTTGATCGCTCGGGGGCTGTCCAATACGGAGATCGCGAGCAGGCTCACGATCAC
GGATCACACCGTGAAGACCCATATCAACCGGCTGTTCGCGAAGCTGAAGCTGCGGGATCGAGCACAGGCCGTGATCGTGG
CTTACGAGTTGGGGCTGGTGCGAGTGGAGGGCAGGGCCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-122)

Bacterial regulatory proteins, luxR family (GerE)

(160-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.121

94.273

0.388