Detailed information NTG0651275

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L3474_RS09055
• Genome accession: NZ_CP091450
• Coordinates: 1783100..1784137 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 3641/15
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1778100..1789137

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3474_RS09030 (L3474_08965)	-	1778839..1780170 (-)	1332	WP_000390039.1	hemolysin family protein	-
L3474_RS09035 (L3474_08970)	endA	1780461..1781285 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
L3474_RS09040 (L3474_08975)	-	1781324..1781512 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
L3474_RS09045 (L3474_08980)	murA	1781505..1782788 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
L3474_RS09050 (L3474_08985)	-	1782812..1783042 (-)	231	WP_000615437.1	DUF1146 family protein	-
L3474_RS09055 (L3474_08990)	sepM	1783100..1784137 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
L3474_RS09060 (L3474_08995)	coaD	1784121..1784609 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
L3474_RS09065 (L3474_09000)	rsmD	1784599..1785138 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L3474_RS09070 (L3474_09005)	asnA	1785203..1786195 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
L3474_RS09075 (L3474_09010)	-	1786307..1786990 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
L3474_RS09080 (L3474_09015)	-	1787046..1787786 (-)	741	WP_000152701.1	RNA methyltransferase	-
L3474_RS09085 (L3474_09020)	-	1787820..1788098 (+)	279	WP_001174613.1	acylphosphatase	-
L3474_RS09090 (L3474_09025)	yidC	1788176..1789102 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=651275 L3474_RS09055 WP_000727280.1 1783100..1784137(-) (sepM) [Streptococcus pneumoniae strain 3641/15]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=651275 L3474_RS09055 WP_000727280.1 1783100..1784137(-) (sepM) [Streptococcus pneumoniae strain 3641/15]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591