Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA37_RS18120 Genome accession   NZ_CP108006
Coordinates   4055049..4055708 (-) Length   219 a.a.
NCBI ID   WP_266906488.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00335     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4050049..4060708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA37_RS18090 (OHA37_18090) - 4050097..4050333 (+) 237 WP_266906476.1 hypothetical protein -
  OHA37_RS18095 (OHA37_18095) - 4050400..4052493 (-) 2094 WP_266906478.1 SpoIIE family protein phosphatase -
  OHA37_RS18100 (OHA37_18100) - 4053003..4053578 (+) 576 WP_266906480.1 DUF5994 family protein -
  OHA37_RS18105 (OHA37_18105) - 4053672..4053938 (+) 267 WP_266906482.1 hypothetical protein -
  OHA37_RS18110 (OHA37_18110) - 4053990..4054262 (+) 273 WP_266906484.1 hypothetical protein -
  OHA37_RS18115 (OHA37_18115) - 4054322..4054924 (-) 603 WP_266906486.1 barstar family protein -
  OHA37_RS18120 (OHA37_18120) vraR 4055049..4055708 (-) 660 WP_266906488.1 response regulator transcription factor Regulator
  OHA37_RS18125 (OHA37_18125) - 4055705..4056853 (-) 1149 WP_266906490.1 histidine kinase -
  OHA37_RS18130 (OHA37_18130) - 4057059..4057412 (+) 354 WP_266906492.1 DUF6223 family protein -
  OHA37_RS18135 (OHA37_18135) - 4057541..4058098 (+) 558 WP_266906494.1 hypothetical protein -
  OHA37_RS18140 (OHA37_18140) - 4058291..4059079 (+) 789 WP_266906496.1 hypothetical protein -
  OHA37_RS18145 (OHA37_18145) - 4059105..4060274 (+) 1170 WP_266906498.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24010.78 Da        Isoelectric Point: 5.6249

>NTDB_id=651258 OHA37_RS18120 WP_266906488.1 4055049..4055708(-) (vraR) [Streptomyces sp. NBC_00335]
MIRVLLVDDQPLIRSGFRAFLDLEDDIEVVAEAADGREGLALARQHLPDVALIDIQMPVLDGIETTRRIAADPELAGVHV
VILTNYGLDEYVFDALSAGAAGFLVKDILPEDFLHAVRVAARGDALLAPSITRKLINRYVTQPLPTDTRTALKDLTARER
EAVVLVAHGLSNEEIAARMVITPLTAKTHVNRAMTKLHARDRAQLVILAYESGLVIRRS

Nucleotide


Download         Length: 660 bp        

>NTDB_id=651258 OHA37_RS18120 WP_266906488.1 4055049..4055708(-) (vraR) [Streptomyces sp. NBC_00335]
GTGATCCGTGTCCTGCTGGTCGACGACCAGCCGCTCATCCGCAGCGGATTCCGGGCGTTCCTCGACCTCGAAGACGACAT
CGAGGTCGTGGCCGAAGCCGCCGACGGCCGGGAGGGCCTGGCGCTCGCCCGGCAGCACCTGCCCGACGTCGCGCTCATCG
ACATCCAGATGCCGGTCCTCGACGGCATCGAGACGACCCGGCGCATCGCGGCCGACCCGGAACTGGCCGGCGTCCACGTC
GTCATCCTCACCAACTACGGCCTGGACGAGTACGTCTTCGACGCCCTGTCCGCGGGCGCCGCCGGGTTCCTCGTCAAGGA
CATCCTGCCGGAGGACTTCCTGCACGCCGTACGCGTGGCCGCACGCGGTGATGCCCTCCTCGCCCCCTCGATCACCCGCA
AACTGATCAACCGGTACGTCACCCAACCCCTCCCCACCGACACGAGGACGGCCTTGAAGGACCTGACCGCCCGCGAACGC
GAAGCGGTCGTCCTGGTCGCGCACGGCCTGTCCAACGAAGAGATCGCGGCCCGCATGGTCATCACACCCCTGACCGCGAA
GACCCACGTCAACCGGGCCATGACCAAACTCCACGCCCGCGACCGCGCCCAACTGGTGATCCTCGCCTACGAATCGGGCC
TGGTGATCCGGCGCAGCTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

98.174

0.379