Detailed information
Bioinformatically predicted
Overview
| Name | clpC | Type | Regulator |
| Locus tag | L3X15_RS09525 | Genome accession | NZ_CP091423 |
| Coordinates | 1939340..1941793 (-) | Length | 817 a.a. |
| NCBI ID | WP_014636516.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain LSM29 | ||
| Function | degradation of ComW (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1935442..1978669 | 1939340..1941793 | within | 0 |
Gene organization within MGE regions
Location: 1935442..1978669
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L3X15_RS09505 (L3X15_09505) | dusB | 1935442..1936446 (+) | 1005 | WP_012775355.1 | tRNA dihydrouridine synthase DusB | - |
| L3X15_RS09510 (L3X15_09510) | - | 1936592..1937365 (-) | 774 | WP_012027854.1 | NUDIX domain-containing protein | - |
| L3X15_RS09515 (L3X15_09515) | pnuC | 1937358..1938179 (-) | 822 | WP_012027855.1 | nicotinamide riboside transporter PnuC | - |
| L3X15_RS09520 (L3X15_09520) | - | 1938189..1939226 (-) | 1038 | WP_012028524.1 | AAA family ATPase | - |
| L3X15_RS09525 (L3X15_09525) | clpC | 1939340..1941793 (-) | 2454 | WP_014636516.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| L3X15_RS09530 (L3X15_09530) | - | 1941799..1942257 (-) | 459 | WP_012027859.1 | CtsR family transcriptional regulator | - |
| L3X15_RS09535 (L3X15_09535) | - | 1942407..1942745 (+) | 339 | WP_012027860.1 | thioredoxin domain-containing protein | - |
| L3X15_RS09540 (L3X15_09540) | - | 1942745..1943446 (+) | 702 | WP_012027861.1 | hypothetical protein | - |
| L3X15_RS09545 (L3X15_09545) | tsf | 1943709..1944749 (-) | 1041 | WP_012027862.1 | translation elongation factor Ts | - |
| L3X15_RS09550 (L3X15_09550) | rpsB | 1944905..1945681 (-) | 777 | WP_012775356.1 | 30S ribosomal protein S2 | - |
| L3X15_RS09555 (L3X15_09555) | - | 1946028..1946540 (-) | 513 | WP_012775452.1 | adenylate kinase | - |
| L3X15_RS09565 (L3X15_09565) | - | 1947194..1952272 (-) | 5079 | WP_012775357.1 | S8 family serine peptidase | - |
| L3X15_RS09570 (L3X15_09570) | nusG | 1952416..1952955 (-) | 540 | WP_002940254.1 | transcription termination/antitermination protein NusG | - |
| L3X15_RS09575 (L3X15_09575) | secE | 1953065..1953241 (-) | 177 | WP_002940255.1 | preprotein translocase subunit SecE | - |
| L3X15_RS09580 (L3X15_09580) | rpmG | 1953251..1953403 (-) | 153 | WP_002940258.1 | 50S ribosomal protein L33 | - |
| L3X15_RS09585 (L3X15_09585) | pbp2a | 1953437..1955650 (-) | 2214 | WP_012027868.1 | penicillin-binding protein PBP2A | - |
| L3X15_RS09590 (L3X15_09590) | - | 1955803..1956771 (+) | 969 | WP_012027869.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| L3X15_RS09595 (L3X15_09595) | - | 1956773..1957639 (+) | 867 | WP_012027870.1 | RluA family pseudouridine synthase | - |
| L3X15_RS09600 (L3X15_09600) | purR | 1957666..1958478 (-) | 813 | WP_002938438.1 | pur operon repressor | - |
| L3X15_RS09605 (L3X15_09605) | - | 1958580..1959446 (-) | 867 | WP_012027872.1 | aminoglycoside phosphotransferase family protein | - |
| L3X15_RS09610 (L3X15_09610) | - | 1959446..1960387 (-) | 942 | WP_012775359.1 | 3'-5' exoribonuclease YhaM family protein | - |
| L3X15_RS09615 (L3X15_09615) | - | 1960377..1961615 (-) | 1239 | WP_012027874.1 | DNA recombination protein RmuC | - |
| L3X15_RS09620 (L3X15_09620) | - | 1961616..1962248 (-) | 633 | WP_012027875.1 | thiamine diphosphokinase | - |
| L3X15_RS09625 (L3X15_09625) | rpe | 1962241..1962900 (-) | 660 | WP_012027876.1 | ribulose-phosphate 3-epimerase | - |
| L3X15_RS09630 (L3X15_09630) | rsgA | 1962915..1963790 (-) | 876 | WP_012027877.1 | ribosome small subunit-dependent GTPase A | - |
| L3X15_RS09640 (L3X15_09640) | - | 1964687..1966264 (-) | 1578 | WP_012027878.1 | ATP-binding cassette domain-containing protein | - |
| L3X15_RS09645 (L3X15_09645) | - | 1966261..1967502 (-) | 1242 | WP_014636518.1 | radical SAM protein | - |
| L3X15_RS09650 (L3X15_09650) | - | 1967871..1968734 (-) | 864 | WP_012027880.1 | helix-turn-helix domain-containing protein | - |
| L3X15_RS09655 (L3X15_09655) | - | 1969224..1971668 (-) | 2445 | WP_012027881.1 | LTA synthase family protein | - |
| L3X15_RS09660 (L3X15_09660) | - | 1971681..1973411 (-) | 1731 | WP_012775361.1 | membrane protein | - |
| L3X15_RS09665 (L3X15_09665) | rsmA | 1973776..1974648 (-) | 873 | WP_012775362.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
| L3X15_RS09670 (L3X15_09670) | - | 1974668..1975198 (-) | 531 | WP_009910909.1 | DUF1697 domain-containing protein | - |
| L3X15_RS09675 (L3X15_09675) | - | 1975212..1975469 (-) | 258 | WP_012775363.1 | Txe/YoeB family addiction module toxin | - |
| L3X15_RS09680 (L3X15_09680) | - | 1975471..1975731 (-) | 261 | WP_002939010.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| L3X15_RS09685 (L3X15_09685) | - | 1975807..1976262 (-) | 456 | WP_012028534.1 | 8-oxo-dGTP diphosphatase | - |
| L3X15_RS09690 (L3X15_09690) | - | 1976269..1976598 (-) | 330 | WP_012775364.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| L3X15_RS09695 (L3X15_09695) | - | 1976588..1976875 (-) | 288 | WP_012028535.1 | hypothetical protein | - |
| L3X15_RS09700 (L3X15_09700) | - | 1976973..1977341 (-) | 369 | WP_012775453.1 | hypothetical protein | - |
| L3X15_RS09705 (L3X15_09705) | rnmV | 1977334..1977903 (-) | 570 | WP_012775366.1 | ribonuclease M5 | - |
| L3X15_RS09710 (L3X15_09710) | - | 1977887..1978669 (-) | 783 | WP_012028536.1 | TatD family hydrolase | - |
Sequence
Protein
Download Length: 817 a.a. Molecular weight: 90162.56 Da Isoelectric Point: 6.3138
>NTDB_id=651073 L3X15_RS09525 WP_014636516.1 1939340..1941793(-) (clpC) [Streptococcus suis strain LSM29]
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
MKISRGLQGVYEDAQLIAQRYSSDYLETWHLLLAFVINPDTVAGAILAEYPADVLDYERAVYMVMGRRYHEELESFFFLP
SSKRVKELQVFAEKIAEIVKSKGLGTEHIFMGMLLDKRSTASQILDQVGFHFEDSDDKVRFLDLRKNLEAKAGFTKEHLK
AIRTMTKGGKPKQATVGNMMGMTQSQSGGLEDYTRDLTALARSGQLEPVIGRDEEISRMLQILSRKTKNNPVLVGDAGVG
KTALALGLAQRIANGEVPASLVNMRILELDLMNVIAGTRFRGDFEERMNNIINDIEEDGRVILFIDELHTIMGSGSGIDS
ILDAANILKPALSRGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPSVADSVAILQGLKPAYEAHHKVTISDQAVV
TAVAYAKRYLTSKNLPDSAIDLLDEASATVQNRAKGQVEEGGLTALDQALMAGKYKTVTQLLLKAQEAENQATSYSLEVT
EEDILATLSRLSGIPVTKLSQTDAKKYLNLEQELHKRVIGQEEAISAVSRAIRRNQSGIRTGHRPIGSFMFLGPTGVGKT
ELAKALAEILFDDESALIRFDMSEYMEKFATSRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGVLTDRKGRKVDFSNTVIIMTSNLGATALRDDKTVGFGALDLSKSQEHVEKRIFEALKKAYRPEFINRIDEKVVFH
SLTEADMQDVVKVMVKPLIAVAASKGITLKLQASALKLLAKEGYDPEMGARPLRRLLQTKLEDPLAEMLLRGELPAGVTL
KVGVKAEQLKFDSVKAG
Nucleotide
Download Length: 2454 bp
>NTDB_id=651073 L3X15_RS09525 WP_014636516.1 1939340..1941793(-) (clpC) [Streptococcus suis strain LSM29]
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
ATGAAGATTTCAAGAGGGTTACAGGGTGTCTATGAAGATGCTCAATTGATTGCACAGCGTTATAGTAGTGACTATTTGGA
GACCTGGCACTTGTTGTTAGCCTTTGTCATCAATCCAGATACCGTTGCGGGAGCTATTTTAGCAGAATATCCTGCGGATG
TATTGGACTATGAACGTGCAGTTTATATGGTGATGGGGCGGCGTTACCATGAAGAGTTAGAGAGCTTTTTCTTTCTTCCA
TCGTCCAAGCGGGTGAAGGAATTGCAGGTCTTTGCCGAGAAGATTGCGGAGATTGTCAAGAGTAAGGGGCTAGGAACGGA
GCATATTTTCATGGGAATGCTCTTGGACAAGCGTTCGACTGCCTCACAAATTCTGGATCAGGTCGGTTTTCACTTTGAGG
ATTCGGATGATAAGGTTCGTTTTCTGGATTTGCGGAAAAATCTGGAAGCCAAGGCTGGCTTTACCAAGGAGCATCTGAAG
GCTATCCGCACCATGACGAAAGGTGGCAAGCCCAAGCAGGCAACGGTTGGCAATATGATGGGCATGACCCAGTCACAAAG
TGGTGGCTTGGAAGACTATACACGTGATTTGACGGCTTTGGCCCGCTCAGGTCAGTTGGAGCCAGTCATCGGACGGGATG
AGGAAATTTCCCGTATGCTTCAGATTTTGTCGCGGAAAACCAAGAACAATCCTGTCTTGGTTGGAGATGCGGGTGTTGGG
AAAACAGCTCTGGCACTGGGTCTAGCCCAGCGGATTGCTAATGGAGAGGTGCCAGCTAGTCTTGTCAATATGCGGATCTT
GGAATTGGACTTGATGAATGTCATTGCGGGAACGCGTTTCCGTGGGGATTTTGAGGAGCGGATGAACAATATCATCAACG
ATATTGAAGAAGATGGTCGAGTGATTCTCTTCATTGATGAACTCCATACCATTATGGGATCGGGGTCAGGGATTGACTCG
ATCCTGGATGCTGCCAATATTTTGAAGCCTGCTCTGTCCCGTGGGACTTTGCGGACAGTTGGAGCAACGACTCAGGATGA
ATACCAGAAGCATATTGAAAAAGATGCTGCCTTAGTACGTCGATTTGCCAAGGTGACCATTGAGGAACCGAGTGTAGCAG
ACAGCGTAGCAATTTTGCAGGGGTTGAAGCCAGCCTATGAGGCTCACCACAAGGTGACCATTTCGGATCAGGCGGTGGTA
ACGGCGGTAGCCTATGCCAAACGCTATCTGACCAGTAAGAATTTGCCAGATTCGGCTATTGATTTGCTGGATGAAGCCAG
TGCGACGGTTCAAAATCGTGCCAAGGGACAGGTAGAAGAAGGTGGATTGACCGCTTTAGACCAAGCCTTGATGGCTGGGA
AATACAAGACGGTAACGCAGCTCTTGCTTAAGGCTCAAGAGGCGGAAAATCAGGCGACTAGCTATAGCTTGGAAGTCACA
GAAGAAGACATTTTGGCAACCCTCAGTCGCTTGTCAGGTATTCCTGTCACCAAACTGAGTCAGACAGATGCCAAGAAGTA
CCTTAATCTTGAACAGGAATTGCACAAGCGTGTTATCGGGCAGGAAGAGGCGATTTCAGCTGTCAGCCGGGCAATTCGCC
GCAACCAGTCAGGCATTCGCACTGGTCACAGACCGATTGGTTCCTTTATGTTCTTGGGGCCAACAGGTGTCGGTAAGACA
GAATTGGCCAAGGCCTTGGCGGAGATCCTCTTTGATGACGAATCTGCCTTGATTCGTTTTGATATGAGTGAGTATATGGA
GAAATTTGCGACTAGTCGCCTCAACGGTGCTCCTCCAGGCTATGTTGGCTATGAAGAAGGGGGCGAGCTGACAGAAAAAG
TTCGCAACAAGCCATACTCTGTCCTACTTTTTGATGAGGTGGAGAAAGCACATCCAGATATTTTCAATGTTCTTTTGCAG
GTCTTGGATGACGGTGTCTTGACGGACAGAAAAGGTCGCAAGGTTGATTTCTCTAATACGGTCATCATTATGACGTCTAA
CTTAGGGGCAACCGCTTTACGTGATGATAAGACAGTTGGGTTTGGGGCTCTTGATTTGTCTAAGAGTCAGGAACACGTTG
AAAAACGGATTTTTGAGGCGTTGAAGAAGGCCTATCGTCCTGAATTTATTAACCGGATTGATGAAAAAGTGGTCTTCCAT
AGCCTGACAGAAGCAGATATGCAGGATGTGGTCAAGGTCATGGTCAAACCATTGATTGCCGTGGCGGCCAGCAAGGGTAT
TACCCTCAAATTGCAGGCTTCTGCTCTTAAACTCTTGGCCAAAGAAGGCTACGATCCAGAAATGGGTGCCCGCCCACTTC
GTCGCCTCCTCCAAACCAAGTTGGAAGATCCATTGGCAGAAATGCTCTTACGTGGAGAACTGCCAGCTGGTGTGACCTTA
AAAGTAGGGGTCAAGGCCGAGCAGTTGAAGTTTGATAGTGTGAAAGCAGGTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpC | Streptococcus pneumoniae TIGR4 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae Rx1 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus pneumoniae D39 |
71.341 |
99.51 |
0.71 |
| clpC | Streptococcus mutans UA159 |
66.049 |
99.143 |
0.655 |
| clpC | Streptococcus thermophilus LMG 18311 |
64.706 |
99.878 |
0.646 |
| clpC | Streptococcus thermophilus LMD-9 |
64.583 |
99.878 |
0.645 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
48.206 |
100 |
0.493 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.526 |
99.51 |
0.443 |