Detailed information NTG0651015

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L3X06_RS07770
• Genome accession: NZ_CP091422
• Coordinates: 1570166..1571215 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain LSM157
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1565166..1576215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3X06_RS07750 (L3X06_07750)	nadE	1565572..1566396 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
L3X06_RS07755 (L3X06_07755)	-	1567692..1568219 (-)	528	WP_012027591.1	VanZ family protein	-
L3X06_RS07760 (L3X06_07760)	rlmN	1568216..1569328 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
L3X06_RS07765 (L3X06_07765)	-	1569337..1569978 (-)	642	WP_012027595.1	YutD family protein	-
L3X06_RS07770 (L3X06_07770)	sepM	1570166..1571215 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
L3X06_RS07775 (L3X06_07775)	coaD	1571202..1571690 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
L3X06_RS07780 (L3X06_07780)	rsmD	1571680..1572219 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L3X06_RS07785 (L3X06_07785)	-	1572527..1573249 (-)	723	WP_012027598.1	lipoprotein	-
L3X06_RS07790 (L3X06_07790)	-	1573306..1573692 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
L3X06_RS07795 (L3X06_07795)	-	1573692..1573910 (-)	219	WP_004194736.1	YqgQ family protein	-
L3X06_RS07800 (L3X06_07800)	-	1574218..1574820 (-)	603	WP_012027601.1	response regulator transcription factor	-
L3X06_RS07805 (L3X06_07805)	-	1574817..1575911 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=651015 L3X06_RS07770 WP_012775295.1 1570166..1571215(-) (sepM) [Streptococcus suis strain LSM157]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=651015 L3X06_RS07770 WP_012775295.1 1570166..1571215(-) (sepM) [Streptococcus suis strain LSM157]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605