Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA62_RS24140 Genome accession   NZ_CP107998
Coordinates   5435636..5436328 (+) Length   230 a.a.
NCBI ID   WP_328681889.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00343     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5430636..5441328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA62_RS24120 (OHA62_24120) - 5431313..5432212 (-) 900 WP_328681882.1 alpha/beta hydrolase -
  OHA62_RS24125 (OHA62_24125) - 5432270..5432878 (+) 609 WP_328681884.1 TetR/AcrR family transcriptional regulator -
  OHA62_RS24130 (OHA62_24130) - 5433355..5434233 (+) 879 WP_328681885.1 CPBP family intramembrane glutamic endopeptidase -
  OHA62_RS24135 (OHA62_24135) - 5434286..5435632 (+) 1347 WP_328681887.1 histidine kinase -
  OHA62_RS24140 (OHA62_24140) vraR 5435636..5436328 (+) 693 WP_328681889.1 response regulator transcription factor Regulator
  OHA62_RS24145 (OHA62_24145) - 5436650..5437324 (+) 675 WP_328681890.1 hypothetical protein -
  OHA62_RS24150 (OHA62_24150) - 5437321..5437800 (+) 480 WP_328681891.1 NUDIX domain-containing protein -
  OHA62_RS24155 (OHA62_24155) - 5437823..5438368 (+) 546 WP_328681892.1 NADPH-dependent FMN reductase -
  OHA62_RS24160 - 5438844..5439182 (+) 339 Protein_4784 FtsX-like permease family protein -
  OHA62_RS24165 (OHA62_24160) - 5439259..5440938 (-) 1680 WP_328681893.1 carboxylesterase family protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 24744.50 Da        Isoelectric Point: 6.3459

>NTDB_id=651012 OHA62_RS24140 WP_328681889.1 5435636..5436328(+) (vraR) [Streptomyces sp. NBC_00343]
MSDAPPPIRVLVCDDQELVRTGYVTIFSAQPDLEVVGEAENGHAAVEAARRLRPDVVVMDIRMPLLDGIQATRQLAGPGA
GQPPKVLVVTTFNVDAHVYDALRAGASGFLLKDAPPAELVNGIRTVARGEALLAPAVTRHLIGHYAEHLRPAESSRPARE
DVVRALTPRELEVLRQMAEGLSNAEIAAELYITPETVKTYVSRILAKLALRDRVQAVVLAYRVGLASGTP

Nucleotide


Download         Length: 693 bp        

>NTDB_id=651012 OHA62_RS24140 WP_328681889.1 5435636..5436328(+) (vraR) [Streptomyces sp. NBC_00343]
GTGAGCGACGCGCCGCCACCGATCCGTGTGCTCGTCTGCGACGACCAGGAACTGGTGCGGACCGGCTACGTCACCATCTT
CTCGGCCCAACCCGACCTGGAGGTCGTCGGCGAGGCGGAGAACGGGCACGCGGCGGTGGAAGCCGCGCGACGGCTGCGCC
CCGACGTGGTCGTGATGGACATCCGGATGCCCCTCCTCGACGGCATCCAGGCGACCCGGCAACTGGCCGGCCCCGGCGCC
GGGCAACCGCCGAAGGTGCTGGTCGTCACCACGTTCAACGTCGACGCCCATGTCTACGACGCGTTACGCGCCGGAGCCAG
CGGGTTCCTCCTCAAGGACGCGCCGCCCGCGGAACTGGTGAACGGCATCCGGACCGTCGCCCGGGGCGAGGCACTGCTGG
CGCCCGCCGTCACCCGGCACCTCATCGGCCACTACGCCGAGCACCTGCGCCCGGCCGAGTCCTCCCGGCCGGCCCGAGAG
GACGTCGTACGCGCGCTGACGCCCCGCGAACTGGAGGTGCTCCGGCAGATGGCCGAGGGCCTGTCGAACGCGGAGATAGC
GGCGGAGCTGTACATCACCCCCGAGACGGTCAAGACCTATGTCTCGCGCATCCTGGCCAAACTCGCCCTGCGCGACCGGG
TCCAGGCGGTCGTCCTCGCCTACCGGGTCGGACTGGCGTCCGGCACACCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(165-220)

Response regulator receiver domain (Response_reg)

(10-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.813

95.217

0.37