Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA62_RS12070 Genome accession   NZ_CP107998
Coordinates   2866605..2867291 (-) Length   228 a.a.
NCBI ID   WP_328678039.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00343     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2861605..2872291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA62_RS12045 (OHA62_12040) - 2861802..2862680 (-) 879 WP_328678031.1 ABC transporter permease -
  OHA62_RS12050 (OHA62_12045) - 2862670..2863485 (-) 816 WP_328678033.1 ABC transporter ATP-binding protein -
  OHA62_RS12055 (OHA62_12050) - 2863645..2864337 (+) 693 WP_328678035.1 response regulator -
  OHA62_RS12060 (OHA62_12055) - 2864386..2865978 (-) 1593 WP_328678036.1 cation acetate symporter -
  OHA62_RS12065 (OHA62_12060) - 2865975..2866535 (-) 561 WP_328678038.1 DUF485 domain-containing protein -
  OHA62_RS12070 (OHA62_12065) vraR 2866605..2867291 (-) 687 WP_328678039.1 response regulator transcription factor Regulator
  OHA62_RS12075 (OHA62_12070) - 2867288..2868439 (-) 1152 WP_328678041.1 histidine kinase -
  OHA62_RS12080 (OHA62_12075) - 2868436..2868960 (-) 525 WP_328678045.1 DUF1453 domain-containing protein -
  OHA62_RS12085 (OHA62_12080) - 2869303..2871423 (-) 2121 WP_328678046.1 DNA topoisomerase IV subunit B -
  OHA62_RS12090 (OHA62_12085) - 2871867..2872100 (+) 234 WP_033283991.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24280.78 Da        Isoelectric Point: 4.7834

>NTDB_id=650979 OHA62_RS12070 WP_328678039.1 2866605..2867291(-) (vraR) [Streptomyces sp. NBC_00343]
MTDEAVRKPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAVDGDEAVRLVAELAPDVVLMDLRMPRCDGVEATRRIRAE
HPGTQVVVLTTFADDASLFPALRAGARGYLTKDAGGDEIVRAVESVLSGDAGLSPSIQRRLLERLSEPEPQEPSEPAEPP
DGLTAREAEVLLLIAEGLTNQEIARALHVSTATVKTHINNLFAKTGLKDRAQAVRYAYGKGLVRPPAG

Nucleotide


Download         Length: 687 bp        

>NTDB_id=650979 OHA62_RS12070 WP_328678039.1 2866605..2867291(-) (vraR) [Streptomyces sp. NBC_00343]
ATGACGGATGAGGCTGTGAGGAAGCCCGCGAGGGTCGTGGTCGCGGACGACCAGACCGTCGTACGGGAAGGCATCGTGAT
GCTGTTGGGGCTGCTGCCCGGGATCGAGGTCGTCGGCGCCGCGGTCGACGGGGACGAGGCGGTGCGGCTCGTCGCCGAAC
TCGCCCCGGACGTCGTCCTGATGGACCTGCGCATGCCGCGCTGCGACGGTGTCGAGGCGACCCGGCGGATCCGTGCGGAG
CATCCCGGGACCCAGGTCGTGGTGCTCACGACGTTCGCGGACGACGCGTCGCTGTTCCCGGCGCTGCGCGCGGGGGCACG
TGGCTACCTCACCAAGGACGCGGGCGGCGACGAGATCGTACGGGCCGTGGAGAGCGTGCTGTCGGGGGACGCGGGGCTGT
CGCCGAGCATCCAACGGCGGTTGCTGGAGCGCCTGTCGGAGCCCGAGCCGCAGGAGCCGTCGGAGCCCGCCGAGCCGCCG
GACGGGCTCACCGCGCGGGAGGCCGAGGTGTTGCTGCTGATCGCGGAGGGCCTGACCAATCAGGAGATCGCCCGCGCGTT
GCACGTCTCCACGGCGACCGTGAAGACCCACATCAACAACCTGTTCGCCAAGACGGGGCTCAAGGACCGTGCGCAGGCGG
TGCGTTACGCCTACGGCAAGGGACTGGTGCGGCCACCAGCGGGTTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(162-217)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

93.86

0.373