Detailed information NTG0650865

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: L3I92_RS03105
• Genome accession: NZ_CP091412
• Coordinates: 589023..590066 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ATR-20003
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 584023..595066

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L3I92_RS03075 (L3I92_000615)	-	584703..584812 (+)	110	Protein_601	hypothetical protein	-
L3I92_RS03080 (L3I92_000616)	-	584841..585254 (+)	414	WP_001622129.1	hypothetical protein	-
L3I92_RS03085 (L3I92_000617)	-	585432..586418 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
L3I92_RS03090 (L3I92_000618)	map	586949..587707 (+)	759	WP_000636137.1	type I methionyl aminopeptidase	-
L3I92_RS03095 (L3I92_000619)	-	587924..588310 (+)	387	WP_049296041.1	hypothetical protein	-
L3I92_RS03100 (L3I92_000620)	liaF	588325..589026 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
L3I92_RS03105 (L3I92_000621)	vraS	589023..590066 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
L3I92_RS03110 (L3I92_000622)	vraR	590056..590685 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
L3I92_RS03115 (L3I92_000623)	-	590798..592015 (-)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
L3I92_RS03120 (L3I92_000624)	-	592293..592568 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
L3I92_RS03125 (L3I92_000625)	-	592575..593039 (-)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
L3I92_RS03130 (L3I92_000626)	-	593186..593386 (+)	201	WP_000180459.1	DUF1128 family protein	-
L3I92_RS03135 (L3I92_000627)	-	593398..594645 (+)	1248	WP_000656302.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=650865 L3I92_RS03105 WP_001017131.1 589023..590066(+) (vraS) [Staphylococcus aureus strain ATR-20003]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=650865 L3I92_RS03105 WP_001017131.1 589023..590066(+) (vraS) [Staphylococcus aureus strain ATR-20003]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1