Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB28_RS15515 Genome accession   NZ_CP107981
Coordinates   3387917..3388624 (-) Length   235 a.a.
NCBI ID   WP_328632124.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00356     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3382917..3393624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB28_RS15495 (OHB28_15510) - 3383301..3384953 (+) 1653 WP_328632121.1 sensor histidine kinase -
  OHB28_RS15500 (OHB28_15515) - 3384950..3385627 (+) 678 WP_327661152.1 response regulator -
  OHB28_RS15505 (OHB28_15520) - 3385683..3387293 (-) 1611 WP_328632122.1 cation acetate symporter -
  OHB28_RS15510 (OHB28_15525) - 3387290..3387823 (-) 534 WP_328632123.1 DUF485 domain-containing protein -
  OHB28_RS15515 (OHB28_15530) vraR 3387917..3388624 (-) 708 WP_328632124.1 response regulator transcription factor Regulator
  OHB28_RS15520 (OHB28_15535) - 3388621..3389778 (-) 1158 WP_328632125.1 histidine kinase -
  OHB28_RS15525 (OHB28_15540) - 3389775..3390281 (-) 507 WP_328632126.1 DUF1453 domain-containing protein -
  OHB28_RS15530 (OHB28_15545) - 3390466..3392589 (-) 2124 WP_327661158.1 DNA topoisomerase IV subunit B -
  OHB28_RS15535 (OHB28_15550) - 3393030..3393260 (+) 231 WP_266714963.1 hypothetical protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 24971.46 Da        Isoelectric Point: 4.8636

>NTDB_id=650649 OHB28_RS15515 WP_328632124.1 3387917..3388624(-) (vraR) [Streptomyces sp. NBC_00356]
MSGAEAGVRAGRSPARVVVVDDQTVVREGIVMLLGLLPGIEVVGSGGDGDEAVALVAELSPDVVLMDLRMPRCDGAEATR
RIRQEYPGTQVVILTTYADDESLFPALRAGARGYLTKDADGDEIVRAVEGVLSGDAGLSPKIQRRLLERLSQPETTMPDP
IEPPDGLTAREAEVLVLISDGLTNQEIARALHVSTATVKTHINNLFAKAGLKDRAQAVRYAYRHGLAKPPGTSIT

Nucleotide


Download         Length: 708 bp        

>NTDB_id=650649 OHB28_RS15515 WP_328632124.1 3387917..3388624(-) (vraR) [Streptomyces sp. NBC_00356]
ATGAGCGGGGCCGAGGCGGGGGTACGCGCGGGGAGGTCACCGGCCCGCGTCGTGGTGGTCGATGACCAGACGGTGGTGCG
CGAAGGCATCGTGATGCTGCTCGGACTGCTGCCCGGGATCGAGGTCGTCGGCTCCGGGGGAGACGGTGACGAGGCGGTCG
CGCTCGTGGCCGAACTGTCCCCGGACGTCGTCCTGATGGACCTTCGTATGCCGCGCTGCGACGGAGCGGAGGCGACCAGA
CGGATCCGGCAGGAGTACCCGGGCACCCAGGTCGTCATCCTGACCACGTACGCCGACGACGAGTCGCTCTTTCCGGCCCT
CAGGGCGGGAGCGCGCGGCTATCTCACGAAGGATGCCGACGGGGACGAGATCGTCCGGGCGGTGGAGGGCGTGCTGTCCG
GTGACGCGGGTCTCTCGCCGAAGATCCAGCGGCGGCTCCTGGAGAGGCTGTCGCAGCCGGAGACCACCATGCCGGACCCG
ATAGAGCCACCCGACGGGCTCACGGCGCGGGAGGCCGAGGTCCTGGTGCTGATCTCCGACGGCCTGACGAACCAGGAGAT
CGCCCGGGCACTGCATGTCTCCACGGCGACGGTGAAGACCCACATCAACAACCTGTTCGCGAAGGCCGGGCTCAAGGACC
GTGCCCAGGCCGTCCGTTACGCGTATCGGCACGGACTCGCGAAGCCGCCGGGGACGTCCATCACCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-128)

Bacterial regulatory proteins, luxR family (GerE)

(166-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.284

89.787

0.362