Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG996_RS09400 Genome accession   NZ_CP107971
Coordinates   1989533..1990213 (-) Length   226 a.a.
NCBI ID   WP_266524963.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00366     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1984533..1995213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG996_RS09375 (OG996_09375) - 1985322..1985906 (-) 585 WP_266524967.1 sugar kinase -
  OG996_RS09380 (OG996_09380) - 1985903..1987051 (-) 1149 WP_266525819.1 ROK family glucokinase -
  OG996_RS09385 (OG996_09385) - 1987227..1987964 (-) 738 WP_266525817.1 GntR family transcriptional regulator -
  OG996_RS09390 (OG996_09390) - 1988094..1989116 (+) 1023 WP_266524965.1 Gfo/Idh/MocA family oxidoreductase -
  OG996_RS09395 (OG996_09395) - 1989226..1989423 (-) 198 Protein_1873 cytochrome P450 -
  OG996_RS09400 (OG996_09400) vraR 1989533..1990213 (-) 681 WP_266524963.1 response regulator transcription factor Regulator
  OG996_RS09405 (OG996_09405) - 1990261..1991526 (-) 1266 WP_266524961.1 sensor histidine kinase -
  OG996_RS09410 (OG996_09410) - 1991696..1991896 (+) 201 WP_266524959.1 hypothetical protein -
  OG996_RS09415 (OG996_09415) - 1991989..1992384 (-) 396 WP_266524956.1 ribonuclease domain-containing protein -
  OG996_RS09420 (OG996_09420) - 1992517..1993143 (-) 627 WP_266524954.1 dihydrofolate reductase family protein -
  OG996_RS09425 (OG996_09425) - 1993233..1994045 (-) 813 WP_266524952.1 AIM24 family protein -
  OG996_RS09430 (OG996_09430) - 1994159..1994905 (+) 747 WP_266524950.1 3-oxoacyl-ACP reductase family protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24075.61 Da        Isoelectric Point: 4.9825

>NTDB_id=650478 OG996_RS09400 WP_266524963.1 1989533..1990213(-) (vraR) [Streptomyces sp. NBC_00366]
MTAIRLLLVDDDPLVRAGLSLMMGGADDIEIVGEAADGSEVEALVDRTRPDVVLMDIRMPSVDGLTATERLRGRKDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVDAVRRVAVGDPVLSPTVTRQLMEHAVGGGADTRRTHARVRIAVLND
REREAAVAVGRGLSNAEIAAALFMSVATVKTHVSRILAKLDLNNRVQIALLAYDAGLLEEPDGDGH

Nucleotide


Download         Length: 681 bp        

>NTDB_id=650478 OG996_RS09400 WP_266524963.1 1989533..1990213(-) (vraR) [Streptomyces sp. NBC_00366]
ATGACTGCGATCAGACTGCTCCTCGTCGACGACGACCCCCTGGTACGGGCCGGCCTGTCCCTGATGATGGGCGGCGCCGA
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGCTCCGAGGTCGAGGCGCTCGTCGATCGCACCCGCCCGGACGTGGTCC
TCATGGACATCCGGATGCCGTCGGTGGACGGCCTCACGGCCACCGAACGGCTGCGCGGCCGCAAGGACGCCCCGCAGGTC
GTCGTCCTCACCACCTTCCACGCCGACGAACAGGTGCTGCGCGCCCTGCGCGCGGGTGCCGCCGGATTCGTCCTCAAGGA
CACCCCGCCCGCCGAGATCGTCGACGCGGTGCGTCGGGTCGCGGTCGGTGACCCCGTGCTGTCGCCCACCGTCACACGGC
AGTTGATGGAGCACGCCGTCGGCGGCGGCGCCGACACCCGGCGCACGCACGCGCGCGTGCGCATCGCCGTCCTCAACGAC
CGCGAACGCGAGGCCGCCGTGGCGGTCGGCCGCGGTCTGTCCAACGCCGAGATCGCCGCCGCCCTGTTCATGAGCGTCGC
CACCGTCAAGACCCATGTGTCCCGGATCCTGGCCAAGCTCGACCTCAACAACCGTGTGCAGATCGCCTTGTTGGCGTACG
ACGCGGGACTGCTGGAGGAACCGGACGGCGACGGGCACTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.356

96.903

0.372