Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS41285 Genome accession   NZ_CP107967
Coordinates   8994896..8995561 (+) Length   221 a.a.
NCBI ID   WP_328542961.1    Uniprot ID   A0ABV4SUL8
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8989896..9000561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS41265 (OHT17_41290) - 8990767..8991999 (+) 1233 WP_326716189.1 geranylgeranyl reductase family protein -
  OHT17_RS41270 (OHT17_41295) - 8991983..8992465 (-) 483 WP_326714338.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHT17_RS41275 (OHT17_41300) - 8992727..8993461 (+) 735 WP_326714339.1 TetR/AcrR family transcriptional regulator -
  OHT17_RS41280 (OHT17_41305) - 8993607..8994899 (+) 1293 WP_328542960.1 sensor histidine kinase -
  OHT17_RS41285 (OHT17_41310) vraR 8994896..8995561 (+) 666 WP_328542961.1 response regulator transcription factor Regulator
  OHT17_RS41290 (OHT17_41315) - 8995696..8997207 (-) 1512 WP_326714342.1 MFS transporter -
  OHT17_RS41295 (OHT17_41320) - 8997295..8997699 (+) 405 WP_326714343.1 MarR family transcriptional regulator -
  OHT17_RS41300 (OHT17_41325) - 8997731..8998462 (-) 732 WP_326714344.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHT17_RS41305 (OHT17_41330) - 8998527..8999744 (-) 1218 WP_326714345.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24054.78 Da        Isoelectric Point: 4.8021

>NTDB_id=650371 OHT17_RS41285 WP_328542961.1 8994896..8995561(+) (vraR) [Streptomyces sp. NBC_00371]
MIRVLLADDQSLVRAGFRALLDAQSDIEVVGEASDGDEAVRLVRELRPDVVLMDIRMPVLDGLAATRRISDDAALETVKV
VMLTTFELDEYVFEAIRAGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIAEFAARSKEPAAAESLGQLTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=650371 OHT17_RS41285 WP_328542961.1 8994896..8995561(+) (vraR) [Streptomyces sp. NBC_00371]
TTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTCCGCGCCGGATTCCGGGCGCTGCTCGACGCGCAGAGCGACAT
CGAGGTCGTGGGGGAGGCCTCCGACGGCGACGAGGCGGTGCGCCTCGTACGCGAACTGCGGCCCGACGTCGTCCTGATGG
ACATCCGGATGCCGGTCCTCGACGGGCTCGCAGCGACCCGCCGCATCAGCGACGACGCCGCGCTGGAAACCGTGAAGGTG
GTCATGCTGACCACTTTCGAACTGGACGAGTACGTCTTCGAGGCGATCCGTGCCGGAGCGTCCGGGTTCCTCGTCAAGGA
CACCGAGCCCGAGGAACTGCTGCGCGCCGTGAGGGCGGTGGTGCACGGCGACGCGCTGCTCTCGCCGGGGGTGACCCGCC
GTCTGATCGCCGAGTTCGCGGCGCGCTCCAAGGAGCCCGCGGCGGCCGAGTCGCTCGGGCAGCTCACCGAGCGCGAGCGT
GAGGTGATGGCGCTGGTCGGCATCGGCCTGTCGAACGAGGAGATCGCCCGCCGCCTCGTCGTCAGCCCGCTCACCGCGAA
GACACATGTGAGCCGCACGATGGTGAAGCTCGGCGCGCGTGACCGGGCCCAACTGGTCGTCCTCGCCTACGAGTCCGGGC
TCGTGCGGCCCGGCTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.535

97.285

0.385
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371