Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHT17_RS37675 Genome accession   NZ_CP107967
Coordinates   8217584..8218246 (-) Length   220 a.a.
NCBI ID   WP_328542776.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00371     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8212584..8223246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHT17_RS37640 (OHT17_37660) - 8212741..8213451 (-) 711 WP_326713789.1 winged helix-turn-helix domain-containing protein -
  OHT17_RS37645 (OHT17_37665) - 8213495..8214142 (-) 648 WP_327577162.1 TetR/AcrR family transcriptional regulator -
  OHT17_RS37650 (OHT17_37670) - 8214223..8215374 (+) 1152 WP_327577161.1 acyl-CoA dehydrogenase family protein -
  OHT17_RS37655 (OHT17_37675) - 8215502..8215792 (+) 291 WP_326713792.1 YiaA/YiaB family inner membrane protein -
  OHT17_RS37660 (OHT17_37680) - 8215867..8216505 (+) 639 WP_266668800.1 TetR/AcrR family transcriptional regulator -
  OHT17_RS37665 (OHT17_37685) - 8216518..8216979 (-) 462 WP_266566073.1 MaoC family dehydratase -
  OHT17_RS37670 (OHT17_37690) soxR 8217105..8217572 (+) 468 WP_326713793.1 redox-sensitive transcriptional activator SoxR -
  OHT17_RS37675 (OHT17_37695) vraR 8217584..8218246 (-) 663 WP_328542776.1 response regulator transcription factor Regulator
  OHT17_RS37680 (OHT17_37700) - 8218243..8219463 (-) 1221 WP_327577160.1 sensor histidine kinase -
  OHT17_RS37685 (OHT17_37705) - 8219597..8220535 (+) 939 WP_326713796.1 ATP-binding cassette domain-containing protein -
  OHT17_RS37690 (OHT17_37710) - 8220532..8221374 (+) 843 WP_327577159.1 ABC transporter permease -
  OHT17_RS37695 (OHT17_37715) - 8221497..8222009 (+) 513 WP_327577158.1 hypothetical protein -
  OHT17_RS37700 (OHT17_37720) - 8222131..8222733 (-) 603 WP_327577157.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23417.98 Da        Isoelectric Point: 4.6363

>NTDB_id=650361 OHT17_RS37675 WP_328542776.1 8217584..8218246(-) (vraR) [Streptomyces sp. NBC_00371]
MTVRVVLADDQPLVRSGLRVLIADTPDLEVVGEAANGEEAVRLAREVSPDVIVMDIRMPGMNGIEAMSLVTSGPGATRVL
VLTTFDEDDYVYGALRAGASGFAVKDMALDDILAAIRVVAAGDALIAPGITRRLIADFVGRPEPSPARAPRAVEGITERE
REVLTLVGLGRSNSEIAEELYITVATTKSHVARLFTKLGARDRVQLVIIAYESGLVSAPR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=650361 OHT17_RS37675 WP_328542776.1 8217584..8218246(-) (vraR) [Streptomyces sp. NBC_00371]
ATGACCGTGCGCGTGGTGCTCGCCGACGACCAGCCGCTCGTGCGCTCCGGGCTGCGCGTCCTCATCGCCGACACCCCCGA
TCTGGAGGTCGTCGGGGAGGCCGCGAACGGTGAGGAGGCCGTCCGGCTGGCGAGGGAGGTCAGCCCCGATGTGATCGTGA
TGGACATCCGGATGCCGGGCATGAACGGGATCGAGGCCATGAGCCTGGTCACCTCGGGCCCGGGGGCGACCCGTGTGCTG
GTGCTGACGACCTTCGACGAGGACGACTACGTCTACGGCGCGCTGCGCGCCGGCGCGAGCGGCTTCGCGGTCAAGGACAT
GGCGCTCGACGACATCCTCGCCGCGATCCGGGTCGTCGCCGCCGGGGACGCGCTGATCGCGCCGGGGATCACGCGCCGCC
TCATCGCCGACTTCGTGGGCCGCCCCGAGCCGTCCCCCGCCCGCGCGCCGCGTGCGGTGGAGGGCATCACCGAGCGGGAG
CGCGAGGTGCTGACGCTGGTGGGGCTCGGCCGGTCGAACAGCGAGATCGCCGAAGAGCTGTACATCACCGTGGCCACGAC
CAAGTCGCACGTGGCCCGCCTGTTCACCAAACTGGGCGCCCGGGACCGGGTCCAACTCGTCATCATCGCCTACGAGTCGG
GGCTGGTCTCCGCGCCCCGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(156-210)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.327

98.636

0.368