Detailed information NTG0650268

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: OG842_RS28575
• Genome accession: NZ_CP107960
• Coordinates: 6334380..6335456 (-)
• Length: 358 a.a.
• NCBI ID: WP_266736834.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00376
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 6329380..6340456

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG842_RS28555 (OG842_28550)	-	6329625..6331427 (-)	1803	WP_266736839.1	phosphatidylglycerol lysyltransferase domain-containing protein	-
OG842_RS28560 (OG842_28555)	cobT	6331531..6332643 (-)	1113	WP_266736837.1	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	-
OG842_RS28565 (OG842_28560)	-	6332784..6333986 (-)	1203	WP_266736835.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
OG842_RS28570 (OG842_28565)	-	6334115..6334324 (+)	210	WP_072483289.1	hypothetical protein	-
OG842_RS28575 (OG842_28570)	htrA	6334380..6335456 (-)	1077	WP_266736834.1	trypsin-like peptidase domain-containing protein	Regulator
OG842_RS28580 (OG842_28575)	-	6335554..6336288 (-)	735	WP_266737372.1	methyltransferase domain-containing protein	-
OG842_RS28585 (OG842_28580)	-	6336402..6337001 (-)	600	WP_266737371.1	DUF3043 domain-containing protein	-
OG842_RS28590 (OG842_28585)	-	6337299..6338081 (+)	783	WP_266736832.1	PspA/IM30 family protein	-
OG842_RS28595 (OG842_28590)	-	6338091..6338369 (+)	279	WP_266736830.1	hypothetical protein	-
OG842_RS28600 (OG842_28595)	-	6338564..6339805 (+)	1242	WP_266736828.1	histidine kinase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 36508.37 Da
• Isoelectric Point: 5.4201

>NTDB_id=650268 OG842_RS28575 WP_266736834.1 6334380..6335456(-) (htrA) [Streptomyces sp. NBC_00376]
MDIFHSRARVRRLLLPLAAGVCAIALVSGCSDAASESPRTEPSNPASATQTASDLQSDYQAVIKNVLPSVVQIQAAESLG
SGIVYDTKGHIVTNAHVVGNDKTFKVTVATGEKEQKAMLVASYPEQDLAVIKLDSVPNGLKPAKFGNSEKVEVGQIVLAM
GSPLGLSSSVTQGIVSALGRTVSESRTGGGTGATIANMVQTSAAINPGNSGGALVNLNSEVIGIPTLAATDPELGGSAAP
GIGFAIPVSMVKTVADQIIKNGKVTDSGRAALNITGRTVVDDNYNPAGVALVSVTKDGAADKAGLRPGDIITRIDDQPVT
TITTLSEALASDKPGQKVTVTYLRDGAEKTAQVTLGEI

Nucleotide

• Length: 1077 bp

>NTDB_id=650268 OG842_RS28575 WP_266736834.1 6334380..6335456(-) (htrA) [Streptomyces sp. NBC_00376]
ATGGATATATTCCACTCCCGCGCCCGCGTTCGCCGGCTGCTGCTGCCCCTGGCCGCCGGGGTCTGTGCGATCGCCCTGGT
GAGCGGCTGCTCGGACGCCGCCTCCGAGTCACCAAGGACCGAACCGAGCAATCCGGCCTCCGCCACCCAGACCGCAAGCG
ATCTACAGAGCGACTACCAGGCCGTGATCAAGAACGTGCTGCCGTCGGTGGTGCAGATCCAGGCCGCCGAGAGCCTGGGC
TCCGGCATCGTCTACGACACCAAGGGCCATATCGTCACCAATGCCCATGTGGTCGGCAACGACAAGACGTTCAAGGTCAC
CGTCGCGACCGGCGAGAAGGAGCAGAAGGCCATGCTGGTGGCCTCCTACCCGGAGCAGGATCTGGCCGTCATCAAGCTCG
ACAGCGTGCCGAACGGGCTGAAGCCCGCGAAGTTCGGCAACTCGGAGAAGGTCGAGGTGGGGCAGATCGTACTGGCGATG
GGCTCGCCGCTCGGTCTGTCCTCCAGCGTCACCCAGGGCATCGTCTCGGCGCTCGGCCGGACCGTCAGCGAGAGCCGCAC
GGGCGGCGGCACCGGTGCGACGATCGCGAACATGGTGCAGACCTCGGCCGCGATCAACCCGGGCAACAGCGGGGGTGCGC
TGGTCAACCTGAACAGCGAGGTGATCGGCATCCCGACCCTGGCGGCGACCGACCCGGAGCTGGGCGGCAGCGCGGCGCCG
GGGATCGGGTTCGCGATCCCGGTGTCGATGGTGAAGACGGTCGCCGATCAGATCATCAAGAACGGCAAGGTCACCGACTC
GGGCCGGGCGGCCCTGAACATCACCGGCCGTACGGTCGTCGACGACAACTACAACCCGGCCGGTGTGGCGCTGGTGAGCG
TGACGAAGGACGGCGCCGCGGACAAGGCCGGGCTGCGGCCCGGCGACATCATCACCAGGATCGACGACCAGCCGGTCACG
ACGATCACCACCTTGTCGGAGGCGCTGGCCTCGGACAAGCCGGGCCAGAAGGTCACGGTGACCTATCTGCGCGACGGGGC
GGAGAAGACGGCGCAGGTCACCCTGGGCGAGATCTAG

Domains

Predicted by InterProScan.

• Peptidase family M50 (Peptidase_M50) (243-354)

• PDZ domain (PDZ_2) (286-355)

• Trypsin-like peptidase domain (Trypsin_2) (80-224)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	34.037	100	0.36